Treatments for late-life bipolar disorder

Aziz, Rehan; Lorberg, Boris; Tampi, Rajesh R.

doi:10.1016/j.amjopharm.2006.12.007

Cited by 96 publications

(84 citation statements)

References 92 publications

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“…These requirements are due to factors typical of old age: physical comorbidities (especially chronic diseases) social isolation, cognitive alterations, limitations in performing activities of daily living, polypharmacy, and age-related variations in the response to therapy, among others (2,6) . It can be verified, in the literature, that the specifics of the management of the pharmacological treatment of BAD geriatrics have been little studied in comparison with management in the young population.…”

Section: Introductionmentioning

confidence: 99%

“…It is known that in the United States, the prevalence rates of BAD in the elderly vary between 0.1% and 0.4%. However, this disorder affects around 10% to 25% of all elderly patients with mood disorders and is responsible for 5% of the hospitalizations of elderly due to psychiatric causes in the country (6) . In Brazil, there is no accurate information on the incidence and prevalence of BAD in the elderly.…”

Section: Introductionmentioning

confidence: 99%

“…An advance in the development of scientific knowledge regarding BAD geriatrics and their treatment could provide an improvement in the care to this group (4)(5)(6)9) . The entire context described points to the importance of research on the adherence to pharmacotherapy, as well as the knowledge and difficulties of elderly patients with BAD related to prescription medication, with the aim of providing subsidies for the optimization of the treatment offered to this clientele.…”

Section: Introductionmentioning

confidence: 99%

“…Drug treatment is essential for the control of BAD in all its stages and in all ages (6) . However, the success of pharmacotherapy is conditional on the adherence to medication treatment and there are several factors that act as barriers to the adherence of the person with BAD to the medication.…”

Section: Introductionmentioning

confidence: 99%

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Medication therapy: adherence, knowledge and difficulties of elderly people from bipolar disorder

Cruz

Miranda²,

Vedana

et al. 2011

Rev. Latino-Am. Enfermagem

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This study aimed to verify the adherence, knowledge and the difficulties of elderly patients with Bipolar Affective Disorder (BAD) in relation to the prescribed pharmacological therapy for the control of this disorder. The study included 17 elderly patients with BAD treated at a Mental Health Center. Semi-structured interviews were conducted and scales were applied. The data were analyzed using a quali-quantitative approach. A low level of adherence to the pharmacological treatment and a deficit in knowledge in relation to the medication were identified, especially regarding the dose and frequency of administration. Among the difficulties inherent to the pharmacotherapy, the obligation of polypharmacotherapy, the desire to quit the pharmacological treatment, limitations in the self-administration of the medication, collateral effects, and doubts about the need for the medication were related. Investment is needed in educational activities and in the promotion of adherence that address the difficulties experienced by elderly people with BAD in the following of the pharmacotherapy in order to ensure safety in the medication therapy.Descriptors: Bipolar Disorder; Medication Adherence; Aged. Identificou-se baixo grau de adesão ao tratamento farmacológico e déficit no conhecimento sobre os medicamentos, especialmente sobre as doses e frequência de administração.Entre as dificuldades inerentes à farmacoterapia relataram-se: a obrigatoriedade da polifarmacoterapia, o desejo de encerrar o tratamento farmacológico, limitações na autoadministração dos fármacos, efeitos colaterais e dúvidas sobre a necessidade dos medicamentos. São necessários investimentos em ações educativas e de promoção da adesão que contemplem as dificuldades vivenciadas pelos idosos com TAB, no seguimento da farmacoterapia, para garantia de segurança na terapêutica medicamentosa.Descritores: Transtorno Bipolar; Adesão à Medicação; Idoso. Terapéutica medicamentosa: adhesión, conocimiento y dificultades de personas ancianas portadoras de trastorno bipolarEste estudio tuvo como objetivo verificar la adhesión, el conocimiento y las dificultades de ancianos con Trastorno Afectivo Bipolar (TAB) en relación a la terapéutica medicamentosa prescrita para control del referido trastorno. Participaron del estudio 17 ancianos con TAB atendidos en un Núcleo de Salud Mental. Fueron realizadas entrevistas semiestructuradas y aplicación de escalas. Los datos fueron analizados con abordaje cualitativo-cuantitativo. Se identificó bajo grado de adhesión al tratamiento farmacológico y déficit en el conocimiento sobre los medicamentos, especialmente sobre las dosis y frecuencia de administración. Entre las dificultades inherentes a la fármacoterapia fueron relatadas la obligatoriedad de la polifármacoterapia, el deseo de terminar el tratamiento farmacológico, las limitaciones en la auto-administración de los fármacos, los efectos colaterales y las dudas sobre la necesidad de los medicamentos. Se concluye que son necesarias inversiones en acciones educativas y de promoción...

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Medication therapy: adherence, knowledge and difficulties of elderly people from bipolar disorder

Cruz

Miranda²,

Vedana

et al. 2011

Rev. Latino-Am. Enfermagem

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“…Further, bipolar disorder accounts for 5 to 19% of all mood disorder presentations in older people and an estimated 5% of inpatient psychiatric admissions for older patients. 22,23 Bipolar disorder in younger populations is associated with high levels of disability and is frequently quoted as the psychiatric disorder associated with the highest rate of suicide, with most estimates of the lifetime risk between 12 and 20%.…”

Section: Mood Stabilisersmentioning

confidence: 99%

Psychotropic Medication Use in Older People

Hopwood

2007

Pharmacy Practice and Res

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Older people have high rates of mental health disorders such as mood and anxiety disorders, bipolar affective disorder, psychotic disorders, and dementia. All of these disorders are associated with significant morbidity and mortality and have been historically under-recognised and under-treated. Recent advances in psychopharmacology have brought great benefit to many young patients with these conditions where they are supported by a clear evidence base. To date, this evidence base has been incompletely developed for older people leaving the prescriber with many difficult decisions. There is moderate and growing evidence supporting the use of antidepressants in this population. The use of mood stabilisers and antipsychotics for indications other than the behavioural and psychological symptoms of dementia currently occurs in the absence of effective evidence. J Pharm Pract Res 2007; 37: 153-6.

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