Treatment with antidepressive drugs improved quality of life in chronic hemodialysis patients

Türk, Süleyman; Atalay, Hüseyin; Altıntepe, Lütfullah; Güney, İ̇brahim; Okudan, Nilsel; Hz, Tonbul; Gökbel, Hakkı; Kucur, Rahim; Yeksan, Mehdi; Yildiz, Alaattin

doi:10.5414/cnp65113

Cited by 42 publications

(30 citation statements)

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“…[14][15][16] That study's conclusions were similar to ours: it was found that the QoL parameters were improved after antidepressant treatment with sertraline. [30] The main limitation of our study is the lack of a control group in the treatment period. Because the number of patients with depression in our study group was small, we did not attempt to have subgroups treated with antidepressants other than citalopram.…”

Section: Discussionmentioning

confidence: 96%

Antidepressant Treatment Increases Quality of Life in Patients with Chronic Renal Failure

et al. 2007

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Section: Discussionmentioning

confidence: 96%

Antidepressant Treatment Increases Quality of Life in Patients with Chronic Renal Failure

et al. 2007

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“…Improvement of ED is associated with marked improvement in depressive symptoms and QOL assessments. [2,[18][19][20] Guan et al showed that anemia, depression, and use of beta blocker were risk factors for decreased libido in female patients with chronic renal insufficiency. In this study, the main manifestations of SD in female patients were "decreased libido, lack of orgasm and no feeling of sex pleasure."…”

Section: Discussionmentioning

confidence: 99%

Female Sexual Dysfunction in Peritoneal Dialysis and Hemodialysis Patients

et al. 2009

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Background. Sexual dysfunction (SD) is a common problem in end-stage renal disease (ESRD). In contrast to basic and clinical research in the field of male SD, the sexual problems of women have received relatively little attention and are often under-treated. We evaluated sexual function in female ESRD patients using the validated Female Sexual Function Index (FSFI) and relation with QOL, depression, and some laboratory parameters. Methods. 117 ESRD patients (85 peritoneal dialysis [PD], 32 hemodialysis [HD], mean age 48.5 ± 13.9 years) were enrolled. All patients had been dialyzed (PD or HD) for more than three months. In addition, an age-matched married control group of 48 subjects (mean age 47.1 ± 12.7 years) were enrolled in the study. All patients were asked to complete three questionnaires of the FSFI, Beck Depression Index (BDI) and SF-36. Results. Female sexual dysfunction was found in 80 of the 85 peritoneal dialysis patients (94.1%) and all of the HD patients (100%), but in only 22 subjects of the control group (45.8%). A significant negative correlation was found between total FSFI score and age (r = −0.288, p = 0.002), BDI score (r = −0.471, p < 0.001), mental-physical component score of QOL (r = −0.463, p < 0.001 and r = −0.491, p < 0.001, respectively) in PD and HD patients. The rates of depression were 75.3, 43.8, and 4.2% in the PD and HD patients and control subjects, respectively. Conclusion. Female sexual dysfunction is common problem ESRD. This problem especially related with depression and QOL. Thus, sexual function should be evaluated in female subjects to determine its impact on quality of life.

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“…Furthermore, selected HRQOL problems are potentially treatable. For example, treatment algorithms for depression in dialysis patients have been proposed (43,44) and sleep disturbances can be addressed.…”

Section: Discussionmentioning

confidence: 99%

Health-related Quality of Life in CKD Patients

Mujais

Story

Brouillette

et al. 2009

Clinical Journal of the American Society of Nephrology

239

227

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Background and objectives: Very few large-scale studies have investigated the determinants of health-related quality of life (HRQOL) in chronic kidney disease (CKD) patients not on dialysis or the evolution of HRQOL over time.Design and setting: A prospective evaluation was undertaken of HRQOL in a cohort of 1186 CKD patients cared for in nephrology clinics in North America. Baseline and follow-up HRQOL were evaluated using the validated Kidney Disease Quality Of Life instrument.Results: Baseline measures of HRQOL were reduced in CKD patients in proportion to the severity grade of CKD. Physical functioning score declined progressively with more advanced stages of CKD and so did the score for role-physical. Female gender and the presence of diabetes and a history of cardiovascular co-morbidities were also associated with reduced HRQOL (physical composite score: male: 41.0 ؎ 10.2; female: 37.7 ؎ 10.8; P < 0.0001; diabetic: 37.3 ؎ 10.6; nondiabetic: 41.6 ؎ 10.2; P < 0.0001; history of congestive heart failure, yes: 35.4 ؎ 9.7; no: 40.3 ؎ 10.6; P < 0.0001; history of myocardial infarction, yes: 36.1 ؎ 10.0; no: 40.2 ؎ 10.6; P < 0.0001). Anemia and beta blocker usage were also associated with lower HRQOL scores. HRQOL measures declined over time in this population. The main correlates of change over time were age, albumin level and co-existent co-morbidities.Conclusions: These observations highlight the profound impact CKD has on HRQOL and suggest potential areas that can be targeted for therapeutic intervention.

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Treatment with antidepressive drugs improved quality of life in chronic hemodialysis patients

Cited by 42 publications

References 0 publications

Antidepressant Treatment Increases Quality of Life in Patients with Chronic Renal Failure

Antidepressant Treatment Increases Quality of Life in Patients with Chronic Renal Failure

Female Sexual Dysfunction in Peritoneal Dialysis and Hemodialysis Patients

Health-related Quality of Life in CKD Patients

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