2013
DOI: 10.1001/jamaophthalmol.2013.147
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Treatment With 9-cisβ-Carotene–Rich Powder in Patients With Retinitis Pigmentosa

Abstract: IMPORTANCE Retinitis pigmentosa (RP) is the leading cause of incurable inherited blindness in the developed world, with an estimated prevalence of 1 in 3500 individuals. Therefore, it is important to develop new treatments for this disease. OBJECTIVE To determine the effect of oral treatment with 9-cis β-carotene on visual function of patients with RP. DESIGN Randomized, double-masked, placebo-controlled, crossover clinical trial. SETTING University tertiary medical facility. PARTICIPANTS Thirty-four patients … Show more

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Cited by 63 publications
(62 citation statements)
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References 35 publications
(44 reference statements)
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“…Finally, 8 studies informed in 13 articles were included in the present review. [9][10][11][12][13][14][15][16][17][18][19][20][21] Characteristics of studies…”
Section: Resultsmentioning
confidence: 99%
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“…Finally, 8 studies informed in 13 articles were included in the present review. [9][10][11][12][13][14][15][16][17][18][19][20][21] Characteristics of studies…”
Section: Resultsmentioning
confidence: 99%
“…All are randomised controlled trials, with a parallel design, 9,10,13,14,16 a crossover design, 11,19,18 or a factorial design. 12 Except Lee et al which studied Best disease, 18 all included studies are on RP.…”
Section: Resultsmentioning
confidence: 99%
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