Treatment Variations in Cerebral Venous Thrombosis: An International Survey

Coutinho, Jonathan M.; Seelig, R; Bousser, Marie‐Germaine; Canhão, Patrı́cia; Ferro, José M.; Stam, Jan

doi:10.1159/000330646

Cited by 33 publications

(18 citation statements)

References 10 publications

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“…For individual physician management, our survey found that most would treat CVST with LMWH, in line with European Federation of the Neurological Societies (EFNS) guidelines3 and in contrast to a previous international survey of neurologists4 where there remained a preference for UFH. Reasons for this difference may reflect a change in practice since the publication of EFNS guidelines or that the current survey sampled from a single nation where practice may be more homogeneous.…”

Section: Discussionsupporting

confidence: 74%

Organisation of services and clinical practice in acute cerebral venous sinus thrombosis: a UK survey

Lavin

Holland

Punter

2017

J Neurol Neurosurg Psychiatry

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Section: Discussionsupporting

confidence: 74%

Organisation of services and clinical practice in acute cerebral venous sinus thrombosis: a UK survey

Lavin

Holland

Punter

2017

J Neurol Neurosurg Psychiatry

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“…However, while evidence-based guidelines advocate the use of LMWH, the majority uses UFH. [100] Other advantages of LMWH in therapeutic doses are that it provides more steady anticoagulation and does not require dosage adjustment based on coagulation times. [5] UFH is administered intravenously at an initial dose of 5000 UI, and then the infusion is maintained at 1000 UI/h or a response dose to achieve an activated partial thromboplastin time of 60-80s.…”

Section: Anticoagulationmentioning

confidence: 99%

“…Endovascular thrombolysis is generally reserved for severe cases, but no randomized trials have been performed. [100] It seems that both endovascular thrombolysis and decompressive craniectomy are increasingly used. In the ISCVT study, 2% of patients received thrombolysis and 1% of patients received decompressive craniectomy;[8] in the international survey mentioned above, 43% of physicians had used either therapy during the last 5 years.…”

Section: Endovascular and Surgical Managementmentioning

confidence: 99%

Cerebral sinus venous thrombosis

Alvis-Miranda¹,

Castellar-Leones²,

Alcalá-Cerra

et al. 2013

Journal of Neurosciences in Rural Practice

109

129

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Cerebral sinus venous thrombosis (CSVT) is a rare phenomenon that can be seen with some frequency in young patients. CSVT is a multifactorial condition with gender-related specific causes, with a wide clinical presentation, the leading causes differ between developed and developing countries, converting CSVT in a condition characterized by a highly variable clinical spectra, difficult diagnosis, variable etiologies and prognosis that requires fine medical skills and a high suspicious index. Patients who presents with CSVT should underwent to CT-scan venography (CVT) and to the proper inquiry of the generating cause. This disease can affect the cerebral venous drainage and related anatomical structure. The symptoms may appear in relation to increased intracranial pressure imitating a pseudotumorcerebri. Prognosis depends on the early detection. Correcting the cause, generally the complications can be prevented. Mortality trends have diminished, and with the new technologies, surely it will continue. This work aims to review current knowledge about CSVT including its pathogenesis, etiology, clinical manifestations, diagnosis, and treatment.

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“…This variation is likely to affect the number of patients eligible for IVT and may have an effect on clinical outcome. The influence and presence of this variation have been noted in other studies [4,5,6]. IST-3 shows that aged patients (>80) benefit from thrombolysis compared to placebo [7].…”

Section: Discussionmentioning

confidence: 67%

Variation in Clinical Practice of Intravenous Thrombolysis in Stroke in the Netherlands

Bauer

Limburg²,

Visser³

2013

Cerebrovasc Dis Extra

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In the Netherlands in 2010, 11% of patients with ischemic stroke received intravenous thrombolysis (IVT), varying from 4 to 26% between hospitals. The aim of this study was to investigate variation in clinical practice and organization of IVT in relationship to performance and outcome. In all 84 Dutch hospitals performing IVT, a stroke neurologist was approached using a web-based survey. The response rate was 82%. The study showed considerable variation. For example, door-to-needle time ranged from 25 to 80 min. High blood pressure was actively lowered before performing IVT by 57% of neurologists, while 35% chose to wait. 28% started IVT without knowledge of laboratory results. Better follow-up data are needed to see whether this variation results in differences in outcome.

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Treatment Variations in Cerebral Venous Thrombosis: An International Survey

Cited by 33 publications

References 10 publications

Organisation of services and clinical practice in acute cerebral venous sinus thrombosis: a UK survey

Organisation of services and clinical practice in acute cerebral venous sinus thrombosis: a UK survey

Cerebral sinus venous thrombosis

Variation in Clinical Practice of Intravenous Thrombolysis in Stroke in the Netherlands

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