Treatment Update of Port-Wine Stain

Wang, Jordan V; Geronemus, Roy G.

doi:10.36849/jdd.6264

Cited by 1 publication

(2 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 20 ] Combination therapies such as PDL with imiquimod and rapamycin have shown promising results in improving treatment outcomes. [ 21 22 ] Photodynamic therapy (PDT) is yet another two-step treatment method for PWS that acts via free-radical damage to the endothelial cells. It has site-specific action, with damage being limited only to photoilluminated areas post-exposure to a photosensitizer.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Vascular Malformations

Bhari,

Agarwal,

Asritha

et al. 2024

Indian Dermatology Online Journal

View full text Add to dashboard Cite

Vascular malformations are intricate anomalies of the circulatory system, presenting a diverse array of clinical manifestations, and posing significant challenges in diagnosis and treatment. The pathogenesis of vascular malformations is explored through the lens of genetic and molecular mechanisms, shedding light on the pivotal role of somatic mutations and dysregulated signaling pathways. Clinical presentations of vascular malformations are widely variable, ranging from cosmetic concerns to life-threatening complications. The utility of imaging techniques, such as magnetic resonance imaging (MRI), computed tomography (CT), and angiography, are discussed in detail, emphasizing their role in precise delineation and characterization. Therapeutic strategies for vascular malformations are multifaceted, considering factors such as lesion size, location, potential complications, and patient-specific factors. Traditional interventions, including surgical excision and embolization, are appraised alongside emerging approaches like targeted molecular therapies and minimally invasive procedures. The manuscript underscores the need for an individualized treatment approach, optimizing outcomes while minimizing risks and complications. In summation, this manuscript offers a comprehensive analysis of vascular malformations, encompassing their underlying pathogenesis, clinical nuances, diagnostic methods, and therapeutic considerations. By synthesizing current knowledge and highlighting gaps in understanding, this review serves as a valuable resource for clinicians, researchers, and medical practitioners, fostering an enhanced comprehension of vascular malformations and paving the way for improved patient care and innovative research endeavors.

show abstract

Section: Introductionmentioning

confidence: 99%

“…[ 20 ] Combination therapies such as PDL with imiquimod and rapamycin have shown promising results in improving treatment outcomes. [ 21 22 ]…”

Section: Introductionmentioning

confidence: 99%