Treatment trials of epizootic lymphangitis with local medicinal plants: a review.

Asfaw, Mersha; Fentahun, Tewodros

doi:10.51227/ojafr.2020.22

Cited by 5 publications

(1 citation statement)

References 19 publications

(28 reference statements)

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“…Sensitivity of the organism to amphotericin B, griseofulvin, nystatin, clotrimazole, and local medicinal plants has been reported. However, in most areas, epizootic lymphangitis is a notifiable disease, and treatment is not allowed, and thereby, diseased animals must be forsaking [ 8 , 16 , 17 ]. Prevention and control measures were carried out, and thiopental sodium 20 ml IV at the jugular vein and potassium chloride 60 ml IV at the jugular vein were used for euthanasia purposes for that horse that was affected by epizootic lymphangitis.…”

Section: Discussionmentioning

confidence: 99%

Ulcerative and Spreading Nodular Lesion of Epizootic Lymphangitis in Adult Black Horse in Gondar, Ethiopia: Case Report and Wound Treatment

Abebaw

2024

Case Reports in Veterinary Medicine

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An adult male black horse was presented to the UOG veterinary clinic with swelling, discharge, and skin wounds on the chest wall and the right front leg; then, it goes to the lateral and medial hind leg. Inspection and palpation were carried out, and we revealed that the skin was swelled, thickened and hard on clinical examination. There was also nodule rupture, and discharge on the limb and chest skin. Different therapy was applied starting from washing the wound with water-diluted potassium permanganate and then 0.9% NaCl together with paraffin topically placed on the wound. 10% povidone-iodine was also applied by using gauze. Griseofulvin 750 mg/day for one week was given as antifungal therapy orally. The prognosis was poor due to the long incubation period and high resistance of the causative agent.

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Section: Discussionmentioning

confidence: 99%

Ulcerative and Spreading Nodular Lesion of Epizootic Lymphangitis in Adult Black Horse in Gondar, Ethiopia: Case Report and Wound Treatment

Abebaw

2024

Case Reports in Veterinary Medicine

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The socioeconomic impact of equine epizootic lymphangitis in working equids in low and middle-income countries: A scoping review

Bonsi,

Anderson,

Carder

2024

Journal of Equine Veterinary Science

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Growth inhibitory effect of selected medicinal plants from Southern Ethiopia on the mycelial phase of Histoplasma capsulatum var. farciminosum

Girma,

Chala,

Mekibib

2024

BMC Vet Res

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Background Epizootic lymphangitis is an infectious and chronically debilitating disease of the equines. Histoplasma capsulatum var. farciminosum, a thermally dimorphic fungi, is the causative agent for the disease. In Ethiopia, the disease significantly affects carthorses, posing threats to animal welfare, and resulting in substantial economic losses. Limited availability of widely accessible antifungals in addition to the chronic nature of the disease is the major challenge against management of epizootic lymphangitis. This study aimed to assess the in vitro efficacy of specific local medicinal plant extracts against the mycelial phase development of H. capsulatum var. farciminosum in southern Ethiopia. The leaves of Xanthium strumarium, Kanda (Family Rubiaceae), Croton macrostachyus (Bisana in Amharic), and Centella Asiatica (Echere waye as a local name in Zeyissegna) that are traditionally used for the treatment of different skin ailments were collected and extracted for the in vitro trial. Results The study revealed that methanol extracts of Xanthium strumarium, Kanda, Croton macrostachyus, and Centella Asiatica, at minimum inhibitory concentrations of 1.25 mg/ml, 2.5 mg/ml, 2.5 mg/ml, and 5 mg/ml, respectively, inhibited the growth of H. capsulatum var. farciminosum. Conclusion This in vitro finding could serve as significant preliminary data in the exploration of effective alternative treatment options for epizootic lymphangitis. This study provides a crucial foundation for further research aimed at determining the chemical components and in vivo effectiveness of these plant extracts against both the mycelial and yeast forms of Histoplasma capsulatum var. farciminosum.

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Treatment trials of epizootic lymphangitis with local medicinal plants: a review.

Cited by 5 publications

References 19 publications

Ulcerative and Spreading Nodular Lesion of Epizootic Lymphangitis in Adult Black Horse in Gondar, Ethiopia: Case Report and Wound Treatment

Ulcerative and Spreading Nodular Lesion of Epizootic Lymphangitis in Adult Black Horse in Gondar, Ethiopia: Case Report and Wound Treatment

The socioeconomic impact of equine epizootic lymphangitis in working equids in low and middle-income countries: A scoping review

Growth inhibitory effect of selected medicinal plants from Southern Ethiopia on the mycelial phase of Histoplasma capsulatum var. farciminosum

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