Treatment Results of Vocal Process Granuloma: Intubation versus Contact Granuloma

Abstract

Introduction Contact granulomas (CGs) and intubation granulomas (IGs) are known to have different clinical manifestations despite having the same pathological features. Objective The purpose of the present study was to analyze the treatment results for CG and IG and to obtain clinical information. Methods We retrospectively reviewed the medical records of patients diagnosed with vocal process granuloma (VPG) between January 2015 and December 2018. The patient's age, sex, medical history, lesion size, lesion type, reflux finding score (RFS), response to treatment, duration of treatment, and follow-up period were compared. Results Eighteen patients with CG and 14 patients with IG were included in the study. The IG group had more female patients (p = 0.0009), showed better response to proton pump inhibitor (PPI) and steroid inhalation (SI) (p = 0.036), and had a shorter treatment period (p = 0.0029) than the CG group. Five patients who received botulinum toxin injections in their vocal cords had complete remission. Conclusion Compared with CG, IG was more responsive to treatment with PPI and SI and required a shorter duration of treatment.

A Giant Granuloma of the Vocal Process after Double-Lumen Bronchial Catheter Insertion: A Rare Case Report and Literature Review

“…It has been suggested that the treatment of CGs and IGs is similar, with the treatment of CGs being based on conservative vocal therapy (which may include vocal rest and speech therapy), along with the treatment of any potential predisposing causes (e.g., gastroesophageal reflux, etc.). However, according to recent findings, the CGs and IGs groups responded differently to combined drug therapy, with the IGs group responding better to combined PPI and SI therapy than the CGs group [16]. There may be three reasons for this result.…”