Treatment rationale for pathological fractures of the mandible: a series of 44 fractures

Coletti, Domenick P.; Ord, Robert A.

doi:10.1016/j.ijom.2007.09.176

Cited by 69 publications

(132 citation statements)

References 37 publications

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“…Percentage of these traumas was similar to the values given by Gerhards et al (2%) and Coletti and Ord, (1%). The average age of the patients is higher than in the group of the patients treated due to the mandible fractures suffered as a result of an injury (1,6). In the group, researched by us, there was not a single dominating cause of the weakening of the mechanical resistibility of the mandible bones, favourable for fracture.…”

Section: Discussionmentioning

confidence: 86%

“…Al Gahtani and Coletti present two proposals of the classification of the causes of pathological mandibular fractures (tab. 1 and 2) (6,7). Among the numerous causes of pathological fractures, more than 50% are connected with chronic infection-related bone inflammation and osteoradionecrosis.…”

mentioning

confidence: 98%

“…According to epidemiologic research, the two most frequent causes of these injuries are interpersonal violence and road accidents (more than 70% of all the fractures within the mandible) (1)(2)(3)(4)(5). Pathological fractures, in turn, are extremely infrequent and constitute between 1 and 2% (1,6). They are defined as spontaneous or caused by a minor injury break-up of the continuity of the bone due to the pathological process or lesion (1,3,6,7,8).…”

mentioning

confidence: 99%

“…Pathological fractures, in turn, are extremely infrequent and constitute between 1 and 2% (1,6). They are defined as spontaneous or caused by a minor injury break-up of the continuity of the bone due to the pathological process or lesion (1,3,6,7,8). Al Gahtani and Coletti present two proposals of the classification of the causes of pathological mandibular fractures (tab.…”

mentioning

confidence: 99%

“…Among the numerous causes of pathological fractures, more than 50% are connected with chronic infection-related bone inflammation and osteoradionecrosis. Another comparatively numerous group is that of atrophic mandible fractures, followed by the fractures POLSKI PRZEGLĄD CHIRURGICZNY 10.2478/v10035-010-0093-y 2010, 82, 11,[615][616][617][618][619][620] in the course of tumour (primary and metastatic) and iatrogenic fractures connected with the surgical removal of impacted teeth (1,3,6,7,(9)(10)(11)(12)(13)(14)(15).…”

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confidence: 99%

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Pathological Fractures of the Mandible in the Department of Cranio-Maxillofacial Surgery Medical University in Łódź

Tyndorf¹,

Manowska²,

Arkuszewski³

et al. 2010

Polish Journal of Surgery

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Pathological fractures of the mandible are rare, comprising 1-2% of this injuries. the aim of the study was to analyse demographic data, etiology, site and treatment procedures of pathological mandible fractures. material and methods. The retrospective study comprised 17 patients (10 males and 7 females) with pathological mandible fracture. Upon the basis of the medical documentation, demographic data, such as age and sex, were recorded, and so were clinical data: mechanism of the fracture, its cause (pathology, causing lowering the mechanical resistibility of the mandible), location and manner of the treatment. Results. Most common cause of the fracture was presence of odontogenic cyst and mandibular atrophy. Most common mechanism of injury were chewing and falls. Regardless of the causes, the majority of the fractures occurred in the body of mandible. conclusion. Treatment of the mandibular pathological fractures differs according to etiology.

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Section: Discussionmentioning

confidence: 86%

mentioning

confidence: 98%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Pathological Fractures of the Mandible in the Department of Cranio-Maxillofacial Surgery Medical University in Łódź

Tyndorf¹,

Manowska²,

Arkuszewski³

et al. 2010

Polish Journal of Surgery

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Proteins conjugated to poly(butyl cyanoacrylate) nanoparticles as potential neuroprotective agents

Reukov

Maximov

Vertegel

2010

Biotech & Bioengineering

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Poly(butyl cyanoacrylate) (PBCA) nanoparticles (NPs) can penetrate blood-brain barrier providing the means for drug delivery to the central nervous system. Here, we study attachment of superoxide dismutase (SOD) and anti-glutamate N-methyl D-aspartate receptor 1 (NR1) antibody to PBCA NPs with the ultimate goal to design neuroprotective therapeutics for treatment of secondary spinal cord injury. Synthesis of monodispersed, ∼200 nm-diameter PBCA NPs was performed using polymerization at pH 2.0 with Dextran 70,000 as the stabilizer. Sulfo-HSAB spacers were used to covalently attach SOD and NR1 antibodies to the dextran-coated NPs. The prepared protein-NP conjugates possessed SOD activity and were capable of binding to rat cerebellar neurons. Thus, SOD and NR1 antibodies may be simultaneously attached to PBCA NPs while retaining at least a fraction of enzymatic activity and receptor-binding ability. The conjugates showed neuroprotective efficacy in vitro with rat cerebellar cell cultures challenged by superoxide.

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Factors predictive of severity of osteoradionecrosis of the mandible

et al. 2011

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Treatment rationale for pathological fractures of the mandible: a series of 44 fractures

Cited by 69 publications

References 37 publications

Pathological Fractures of the Mandible in the Department of Cranio-Maxillofacial Surgery Medical University in Łódź

Pathological Fractures of the Mandible in the Department of Cranio-Maxillofacial Surgery Medical University in Łódź

Proteins conjugated to poly(butyl cyanoacrylate) nanoparticles as potential neuroprotective agents

Factors predictive of severity of osteoradionecrosis of the mandible

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