Background: The paper contains a brief comprehensive review of new perspective techniques for the cancer detection and treatment in modern diagnostic radiology including stereotactic irradiation, total body irradiation, total skin electron irradiation, intra operative radiotherapy, endocavitary rectal irradiation, conformal radiotherapy, image guided radiotherapy, adaptive radiotherapy, respiratory gated radiotherapy, PET/CT scanners and PET/CT image fusion approaches. The image acquisition, recognition and analyses proper to different techniques, radiation sources, doses and treatment strategies for them, as well as advantages and disadvantages are discussed.