Treatment planning for hyperthermia with ultrasound phased arrays

McGough, Robert J.; Kessler, M.L.; Ebbini, E.S.; Cain, Charles A.

doi:10.1109/58.542051

Cited by 66 publications

(34 citation statements)

References 27 publications

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“…A more precise mathematical consideration of wave propagation effects with full anatomically correct models could make the estimates of bone heating and validation of treatment strategies more accurate. Since bone position varies greatly between patients, a pretreatment determination of individual patient anatomy and treatment planning systems [83] could be used to avoid bone heating, and could be used to choose appropriate treatment parameters specific for each patient [83][84][85].…”

Section: Discussionmentioning

confidence: 99%

Prostate thermal therapy with high intensity transurethral ultrasound: The impact of pelvic bone heating on treatment delivery

Wootton

Ross

Diederich

2007

International Journal of Hyperthermia

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Section: Discussionmentioning

confidence: 99%

Prostate thermal therapy with high intensity transurethral ultrasound: The impact of pelvic bone heating on treatment delivery

Wootton

Ross

Diederich

2007

International Journal of Hyperthermia

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“…A similar ray tracing algorithm for defining effective elements of a transducer array in the planning of ultrasound thermal ablation was described by McGough. 10 The 1208 aperture is much greater than typically required for an ultrasound therapy transducer (equivalent to f-number ¼ 0.6, i.e., the ratio between the focal length and diameter) and was taken to represent the collection of all reasonable transducer placement locations for a smaller transducer pointed directly at the target. To simulate a more realistic size transducer, for each target location and subject, a circular region spanning a 608 solid angle (f-number ¼ 1) was placed within the overall aperture such that the number of unblocked rays was maximized achieving an optimal placement.…”

Section: Methodsmentioning

confidence: 99%

Acoustic Access to the Prostate for Extracorporeal Ultrasound Ablation

Hall

Hempel

Sabb

et al. 2010

Journal of Endourology

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This study aimed to measure acoustic access to the prostate for extracorporeal ultrasound ablation. Both transabdominal and transperineal approaches were considered. The objective was to measure the size and shape of the aperture available for unobstructed targeting of the prostate. CT images of 17 randomly selected men >56 years of age were used to create 3D reconstructions of the lower abdomen and pelvis. Rays were traced from target locations in the prostate toward the perineum and the abdomen. The maximum CT density encountered along each path was recorded; those paths that traversed structures with CT density exceeding a soft tissue threshold were considered to be blocked by bone. Unblocked rays comprised the accessible aperture. The aperture through the perineum was found to be a triangular-shaped region bounded by the lower bones of the pelvis varying significantly in size between subjects. The free aperture through the abdomen was wedge shaped limited by the pubis and also with great subject-to-subject variability. Average unblocked fractions of an f=1 transducer to target base, middle, and apex of the prostate along the urethra from the perineum were 77.0%, 94.4%, and 99.6%, respectively. Averages targeting from the abdomen were 86.1%, 52.3%, and 11.0%. Acoustic access to the prostate for therapy through the perineum was judged to be feasible. Access from the abdomen was judged to be sufficient for the base of the prostate, but likely inadequate for the middle and apex.

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“…2 Preferably, such a method would adapt to realistic tissue geometries, facilitate the patient positioning, and estimate the required energy deposition in the target area while minimizing the risk of undesired damage to subcutaneous tissue or critical organs. In this work, we propose a simulation method which allows rapid evaluation of the ultrasonic field in complicated geometries, within a clinically relevant time frame.…”

Section: Introductionmentioning

confidence: 99%

Stochastic ray tracing for simulation of high intensity focal ultrasound therapy

Koskela

Vahala

Greef

et al. 2014

The Journal of the Acoustical Society of America

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An algorithm is presented for rapid simulation of high-intensity focused ultrasound (HIFU) fields. Essentially, the method combines ray tracing with Monte Carlo integration to evaluate the Rayleigh-Sommerfeld integral. A large number of computational particles, phonons, are distributed among the elements of a phase-array transducer. The phonons are emitted into random directions and are propagated along trajectories computed with the ray tracing method. As the simulation progresses, an improving stochastic estimate of the acoustic field is obtained. The method can adapt to complicated geometries, and it is well suited to parallelization. The method is verified against reference simulations and pressure measurements from an ex vivo porcine thoracic tissue sample. Results are presented for acceleration with graphics processing units (GPUs). The method is expected to serve in applications, where flexibility and rapid computation time are crucial, in particular clinical HIFU treatment planning.

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Treatment planning for hyperthermia with ultrasound phased arrays

Cited by 66 publications

References 27 publications

Prostate thermal therapy with high intensity transurethral ultrasound: The impact of pelvic bone heating on treatment delivery

Prostate thermal therapy with high intensity transurethral ultrasound: The impact of pelvic bone heating on treatment delivery

Acoustic Access to the Prostate for Extracorporeal Ultrasound Ablation

Stochastic ray tracing for simulation of high intensity focal ultrasound therapy

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