Treatment Outcomes of Leiomyosarcoma Metastasis Affecting the Brachial Plexus: A Comparative Case Report Using Chat Generative Pre-trained Transformer (ChatGPT)

Abstract

Sarcomas are a rare type of cancer that can develop in various parts of the body, including the brachial plexus. Leiomyosarcomas (LMs) are a subtype of sarcoma that develops in smooth muscle tissue and can metastasize to different parts of the body. In this case report, we present two patients with LM metastasized to the brachial plexus, one treated with CyberKnife (Accuray, Sunnyvale, CA) stereotactic radiosurgery (CK SRS) and the other with surgical resection. The aim of this case report is to present the treatment outcomes and adverse effects of CK SRS and surgical resection in brachial plexus LM metastasis. Patient 1 was a 39year-old female who received CK SRS, and at three months of follow-up, the lesion was smaller, and she reported symptomatic improvement. At 15 months, the lesion was stable in size, and there was no evidence of local invasion of the adjacent vascular structures or nerves. Patient 2 was a 52-year-old male who underwent surgical resection, and at one-month follow-up, the patient was asymptomatic with no recurrence of his symptoms. The size of the residual axillary tumor was stable at three months and showed a slight interval decrease in size at five months of follow-up. He was followed for over 12 months, with no recurrence of his symptoms.Both treatments appear to have been effective in controlling LM growth and relieving symptoms. CK SRS provides a non-invasive option. However, more research is needed to fully understand the effectiveness and safety of these treatments for brachial plexus sarcoma. This case report highlights the importance of considering different treatment options for brachial plexus sarcoma and the need for further studies to understand the best approach for these rare cases.

The Expanding Role of ChatGPT (Chat-Generative Pre-Trained Transformer) in Neurosurgery: A Systematic Review of Literature and Conceptual Framework

“…In the realm of scientific publications, researchers addressed AI-generated research paper fabrication and plagiarism, emphasizing the importance of detecting and preventing AI-generated plagiarism to uphold the integrity of scholarly works [2]. Moreover, ChatGPT was showcased as a valuable tool for enhancing medical case reporting and study data analysis for manuscript production [8,9,11,12]. The impact of ChatGPT on medical education was explored, with discussions centering on strategies for responsible implementation to enhance learning experiences, promote critical thinking, and address individual learning needs in healthcare education [10].…”

“…By providing information on treatment options, potential risks, and benefits, as well as postoperative care, it enhances patient satisfaction and engagement [25]. Notwithstanding these applications, furthermore, ChatGPT has been shown to aid in scientific production, facilitating text generation, with a number of scientific articles being produced by such means, as well as being an adjuvant in education [8][9][10][11][12].…”

“…By generating outlines, identifying relevant literature, and offering suggestions for sentence structure and grammar, ChatGPT can streamline the writing process for researchers. This could significantly reduce the time and effort required to produce high-quality scientific manuscripts, although questions may arise regarding the potential loss of individual creativity [6][7][8][9][10]. This article aims to discuss, therefore, the potential applications of ChatGPT in different neurosurgery topics and its impact on the field.…”