Treatment Outcome and Efficacy of Anti-Tuberculosis Treatment in Tuberculosis Patients Put on Dots in RNTCP in Central India

Abstract

BACKGROUND Tuberculosis (TB) remains a global public health problem and a major cause of death from a single infectious agent among adults in India and other developing countries.Aims & Objectives-The aim of this study is to characterise outcome and efficacy of tuberculosis treatment among patients put on DOTS in RNTCP. MATERIALS AND METHODSThis is a retrospective study of diagnosed TB patients of all age groups attending OPD of various departments of LN Medical College and JK Hospital, Bhopal, MP (India), between the period of January 2012 and October 2015. RESULTSTotal 454 patients were found eligible for this study who were diagnosed and received full course of ATT under DOTS in RNTCP. In different age groups percentages of patients observed were 12.11%, 31.27%, 22.68%, 13.65% and 20.26% in 0 -14 years, 15 -25 years, 26 -35 years, 36 -45 years and above 45 years respectively. CONCLUSIONMaximum patients, 31.27% (142/454) were registered in the age group of 15 -25 years. Overall, treatment outcome were observed as follows-82.81% treated successfully, 7.70% defaulted, 4.18% failed and 3.96% died. Higher percentage of treatment was successful (98.18%) and was observed in the age group of 0 -14 years, whereas higher percentage of both defaulter (14.13%) and mortality (13.04%) with lower treatment success rate (65.21%) was observed in the age group of above 45 years. Higher percentage of defaulter, failure and mortality were observed in males and category I in comparison to females and category II.