Treatment of Wegener's granulomatosis with Imuran

Mucormycosis in a Patient Receiving Azathioprine

“…A conflicting report was published by Bouroncle, who successfully treated a pa¬ tient with Wegener's granuloma using aza¬ thioprine. 4 We feel, as do others, that the histopathologic evidence of tissue invasion by the mycotic organism confirms the diagnosis.…”

Granulomatosis with polyangiitis (Wegener's disease): An updated review of ocular disease manifestations

“…Because of the significant toxicity associated with cyclophosphamide therapy, alternative maintenance therapies have been used. Azathioprine has shown some success, but it is less effective than cyclophosphamide and should only be considered in patients experiencing adverse side effects or when fertility concerns arise (80). Methotrexate has been used in patients with limited GPA, though it is less likely to achieve and sustain remission (81,82).…”

The radiological manifestations of Wegener's granulomatosis

“…Carrington and Liebow (1966) and others (Cassan, Coles, and Harrison, 1970;Israel and Patchefsky, 1971) called attention to a limited form of this disease with characteristic pulmonary lesions but with little or no systemic involvement. In addition, recently Bouroncle, Smith and Cuppage (1967) and Israel and Patchefsky (1971) have indicated that cytotoxic therapy appears to be effective in arresting the disease.…”