Treatment of Transitional Cell Carcinoma of the Ureter: Is the Controversy Justified?

Zungri, E; Chéchile, G; Algaba, F.; Diaz, I Ruiz; Vila, F.; Castro, Catarina

doi:10.1159/000464059

Cited by 68 publications

(22 citation statements)

References 5 publications

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“…This speaks in favor of the use of frozen sections. Aufderklamm and Jakse [4] recommend resection of the distal ureter with UCN for all tumor stages, while Zungri et al [13] do not advise organ-saving procedures for infiltrating ureteral carcinomas. In a retro spective study on 38 patients with NUE and 35 patients with kidney preservation, these authors found the conser vative method to produce a 24% longer survival time in patients with stage T2.…”

Section: Discussionmentioning

confidence: 99%

Organ-Sparing Treatment for Ureteral Carcinoma?

Leitenberger¹,

Beyer²,

Altwein³

1996

Eur Urol

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Section: Discussionmentioning

confidence: 99%

Organ-Sparing Treatment for Ureteral Carcinoma?

Leitenberger¹,

Beyer²,

Altwein³

1996

Eur Urol

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“…A prognostically unfavorable sign was penetration of the tumor into the parenchyma or renal pelvis, independent of the tumor grading. Zungri et al [68] also stated that the 5-year survival of nonimmunosuppressed patients following nephroureterectomy was dependent on the tumor stage (pTa, 100%; pT1, 96%; pT2/3, 33%).…”

Section: Discussionmentioning

confidence: 99%

Denovo urothelial carcinoma of the upper and lower urinary tract in kidney ? transplant patients with end-stage analgesic nephropathy

et al. 1995

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Patients with end-stage analgesic nephropathy bear a higher risk for urothelial cancer than do patients with other renal diseases. In a retrospective study in patients with analgesic nephropathy and kidney transplants we analyzed the prevalence and clinical course of de novo urothelial cancer. Diagnosis of analgesic nephropathy was based on the patients' history and clinical data. Only patients under cyclosporine treatment were included. Between 1968 and 1993, 2,371 kidney transplants were performed on 2,072 patients in the Department of Abdominal and Transplant Surgery. The prevalence of analgesic nephropathy was 3.1%. Of 65 patients with analgesic nephropathy and kidney transplants, 10 (15.4%) developed urothelial carcinoma; 10.8%, bladder cancer; and 9.1%, renal pelvic cancer. The mean age at diagnosis was 56.1 years. Urothelial cancer occurred on average at 33.6 months posttransplantation. On average, 6 of 10 patients with urothelial cancer died of the disease at 16.9 months after the diagnosis. All patients with urothelial bladder cancer had a muscle-infiltrating tumor of moderate or high grade. Since urothelial renal pelvic cancer occurred in 9.1% of our patients with analgesic nephropathy and urological screening is insufficient in patients on dialysis, we suggest that prophylactic nephroureterectomy be performed on one side before transplantation and on the contralateral side at 3-6 months after transplantation. An aggressive approach is indicated in patients with urothelial cancer of the bladder.

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“…We chose to carry out pyelic mass resection and pyeloureterostomy since this more conservative approach was further justified by the patient's age, her multiple pathological conditions and her refusal to undergo chronic dialysis due to her place of residence and way of life. Preservation of the kidney and ureter has provided her with a good quality of life, free of dialysis treatments [5]. Adjuvant treatment after surgery may be not necessary due to the small functional renal mass and the unfavorable prognosis of the patient.…”

Section: Discussionmentioning

confidence: 99%

Pyelic Metastasis from a Renal Cell Carcinoma following Partial Nephrectomy

Silva¹,

Telo²,

Pampin³

et al. 1999

Urol Int

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The majority of ureteropelvic metastatic tumors are of non-urologic origin. A case of metastatic clear cell adenocarcinoma to the renal pelvis in a patient with a bilateral, asynchronous renal tumor is presented. Conservative surgical treatment involved open pyelotomy and local resection of the tumor. At the 12-month follow-up, the patient is alive, asymptomatic and not on dialysis. The hypothesis for the mechanisms of dissemination and the relevance of conservative treatment are discussed.

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Treatment of Transitional Cell Carcinoma of the Ureter: Is the Controversy Justified?

Cited by 68 publications

References 5 publications

Organ-Sparing Treatment for Ureteral Carcinoma?

Organ-Sparing Treatment for Ureteral Carcinoma?

Denovo urothelial carcinoma of the upper and lower urinary tract in kidney ? transplant patients with end-stage analgesic nephropathy

Pyelic Metastasis from a Renal Cell Carcinoma following Partial Nephrectomy

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