Treatment of Specific NDMA Precursors by Biofiltration

Marti, Erica J.; Dickenson, Eric; Trenholm, Rebecca A.; Batista, Jacimaria R.

doi:10.5942/jawwa.2017.109.0070

Cited by 8 publications

(3 citation statements)

References 64 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is noteworthy that the levels of industrial TMDS produced in 2014 in Japan were 150 tons . In addition, TMDS and related semicarbazides have low removal after biological treatment, including biofiltration. , PCCID 141210417 has a similar structure as TMDS and could therefore exhibit poor removal during conventional wastewater or sewage treatment. Thus, PCCID 141210417 may contribute to NDMA formation at STPs.…”

Section: Resultsmentioning

confidence: 99%

“…NDMA precursors are presumably tertiary amines (p K a range 6–10) with a basic moiety, which control their capture using an MCX cartridge at pH 3 . In addition, precursors bearing DMH have a typical p K a range 1–4. , By analogy, low recovery of precursors on the MCX cartridge can reveal that the precursors are not tertiary amines [e.g., compounds bearing (CH 3 ) 2 N–S(O 2 )–N] and are plausibly compounds bearing DMH (neutral at pH 3). Parallel to SPE, evaporation was employed to determine which method recovered well the O 3 -reactive precursors.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Predictable Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry Fragmentation of Ozone-Reactive N-Nitrosodimethylamine Precursors Coupled with In Silico Fragmentation and Ion Mobility-Quadrupole Time-of-Flight Facilitates Their Identification in Sewage

Hinneh

Kosaka

Echigo

et al. 2022

Environ. Sci. Technol.

View full text Add to dashboard Cite

This study investigated the liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF/MS) fragmentation of 10 potent model ozone (O 3 )-reactive Nnitrosodimethylamine (NDMA) precursors bearing (CH 3 ) 2 N−N or (CH 3 ) 2 N−(SO 2 )−N. Fragments (m/z 61.0766, 60.0688 Da loss, and 72.0688 Da loss) were discovered as pertinent diagnostic fragments for precursors bearing (CH 3 ) 2 N−N, whereas a loss of 108.0119 Da was consistent for precursors bearing (CH 3 ) 2 N− S(O 2 )−N. Using the fragments as structural hints on a sewage fraction with a high concentration of O 3 -reactive precursors, peaks of precursors sharing m/z 61.0766, a 60.0688 Da loss, or both were flagged. Then, using in silico fragmenters and (CH 3 ) 2 N−N as a substructure filter on online-chemical structure databases, we identified PubChem's compound identifier (PCCID) 141210417 and 1,1,1′,1′-tetramethyl-4,4′-(methylene-di-p-phenylene)disemicarbazide (TMDS). TMDS was confirmed using an authentic standard, and ion mobility (IM)-QTOF/MS confirmed its rider peak as PCCID 141210417. PCCID 141210417 is an isomer of TMDS, and its environmental occurrence is associated with technical-grade TMDS and industrial effluents. The estimated contribution of TMDS to the total NDMA formation potential of the sewage fraction was 20−24%, which was suggestive of the significance of PCCID 141210417 and other precursors.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Predictable Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry Fragmentation of Ozone-Reactive N-Nitrosodimethylamine Precursors Coupled with In Silico Fragmentation and Ion Mobility-Quadrupole Time-of-Flight Facilitates Their Identification in Sewage

Hinneh

Kosaka

Echigo

et al. 2022

Environ. Sci. Technol.

View full text Add to dashboard Cite

show abstract

“…S6 and S7 . This relatively high performance is likely associated with the trace contaminants (e.g., ranitidine, diphenhydramine, and tetracycline) which are NDMA precursors and are removed effectively with GAC ( Hanigan et al., 2012 ; Marti et al., 2017 ; Mulhern et al., 2017 ).…”

Section: Resultsmentioning

confidence: 99%

Controlling disinfection byproducts from treated wastewater using adsorption with granular activated carbon: Impact of pre-ozonation and pre-chlorination

et al. 2020

Self Cite

View full text Add to dashboard Cite

This study measured chlorine- and chloramine-reactive precursors using formation potential (FP) tests of nine U.S. Environmental Protection Agency (EPA) regulated and 57 unregulated disinfection byproducts (DBPs) in tertiary-filtered wastewater before and after pilot-scale granular activated carbon (GAC) adsorption. Using breakthrough of precursor concentration and of concentration associated calculated cytotoxicity and genotoxicity (by correlating known lethal concentrations reported elsewhere), the performance of three parallel GAC treatment trains were compared against tertiary-filtered wastewater: ozone/GAC, chlorine/GAC, and GAC alone. Results show GAC alone was the primary process, versus ozone or chlorine alone, to remove the largest fraction of total chlorine- and chloramine-reactive DBP precursors and calculated cytotoxicity and genotoxicity potencies. GAC with pre-ozonation removed the most chlorine- and chloramine-reactive DBP precursors followed by GAC with pre-chlorination and lastly GAC without pre-treatment. GAC with pre-ozonation produced an effluent with cytotoxicity and genotoxicity of DBPs from FP that generally matched that of GAC without pre-oxidation; meanwhile removal of toxicity was greater by GAC with pre-chlorination. The cytotoxicity and genotoxicity of DBPs from FP tests did not scale with DBP concentration; for example, more than 90% of the calculated cytotoxicity resulted from 20% of the DBPs, principally from haloacetaldehydes, haloacetamides, and haloacetonitriles. The calculated cytotoxicity and genotoxicity from DBPs associated with FP-chloramination were at times higher than with FP-chlorination though the concentration of DBPs was five times higher with FP-chlorination. The removal of DBP precursors using GAC based treatment was at least as effective as removal of DOC (except for halonitromethanes for GAC without pre-oxidation and with pre-chlorination), indicating DOC can be used as an indicator for DBP precursor adsorption efficacy. However, the DOC was not a good surrogate for total cytotoxicity and genotoxicity breakthrough behavior, therefore, unregulated DBPs could have negative health implications that are disconnected from general water quality parameters, such as DOC, and regulated classes of DBPs. Instead, cytotoxicity and genotoxicity correlate with the concentration of specific classes of unregulated DBPs.

show abstract

Impact on Disinfection Byproducts Using Advanced Oxidation Processes for Drinking Water Treatment

Mayer

Ryan

2017

The Handbook of Environmental Chemistry

View full text Add to dashboard Cite

Treatment of Specific NDMA Precursors by Biofiltration

Cited by 8 publications

References 64 publications

Predictable Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry Fragmentation of Ozone-Reactive N-Nitrosodimethylamine Precursors Coupled with In Silico Fragmentation and Ion Mobility-Quadrupole Time-of-Flight Facilitates Their Identification in Sewage

Predictable Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry Fragmentation of Ozone-Reactive N-Nitrosodimethylamine Precursors Coupled with In Silico Fragmentation and Ion Mobility-Quadrupole Time-of-Flight Facilitates Their Identification in Sewage

Controlling disinfection byproducts from treated wastewater using adsorption with granular activated carbon: Impact of pre-ozonation and pre-chlorination

Impact on Disinfection Byproducts Using Advanced Oxidation Processes for Drinking Water Treatment

Contact Info

Product

Resources

About