Treatment of scalp defects with a combination of trephination and platelet-rich plasma

Gökkaya, Ali; Görğü, Metin

doi:10.1016/j.jtv.2020.04.004

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…[ 18 ] Unlike the preparation of platelet-rich fibrin and PRP gel, the PRG used in this study can be prepared only by a single centrifugation for 5 minutes because of the use of centrifuge tubes containing coagulant, which not only shortened the preparation time and improved clinical efficiency but also reduced the risk of infection. Gökkaya et al [ 19 ] reported for the first time a case report in which trephine combined with PRP successfully reconstructed a large area of scalp defect with an exposed skull. In this study, 12 patients received PRG treatment and were finally all healed, with an average healing time of 25.00 ± 5.77 days.…”

Section: Resultsmentioning

confidence: 99%

Platelet-rich gel versus external tissue expansion technique in treating scalp defects: A retrospective study

Ai,

Wang,

2023

Medicine

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Reconstruction of scalp defects is a complicated and challenging procedure for reconstructive surgeons. This retrospective observational study assessed the effectiveness of using platelet-rich gel (PRG) versus the external tissue expansion technique (TET) in reconstructing scalp defects. The clinical data of 24 patients with scalp defects treated with PRG or external TET were collected from September 2018 to March 2022. Data on the wound characteristics, wound healing time, cost of treatment, visual analog scale, and observed wound healing status were collected. The mean wound healing times in the PRG and TET groups were 25.00 ± 5.77 and 13.58 ± 9.68 days, respectively (P < .05). The PRG group was significantly more cost-effective than the TET group (P < .05). TET treatment significantly increased patients’ postoperative pain, which decreased over time (P < .05), while PRG treatment caused no significant change in pain (P > .05). The 2 groups showed no tissue depression or color change after wound healing at follow-up, but the hair growth in the TET group was significantly better than that in the PRG group (P < .05). Compared with TET treatment of scalp defects, PRG is not only simple and painless but also has a low treatment cost and, more importantly, does not involve the risk of surgery and anesthesia. However, using TET to treat scalp defects requires the careful selection of appropriate cases.

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Section: Resultsmentioning

confidence: 99%

Platelet-rich gel versus external tissue expansion technique in treating scalp defects: A retrospective study

Ai,

Wang,

2023

Medicine

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Application of Platelet-Rich Gel in Repairing Scalp Defects Combined with Skull Exposure: A Case Series Analysis

Wang,

2023

Indian J Surg

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Clinical treatment of exposed skull injuries becomes extremely challenging. The current treatment methods for exposed skull injuries are mainly surgical treatments. However, these treatments are not suitable for elderly patients who cannot tolerate anaesthesia. This research aimed to assess the effectiveness of platelet-rich gel (PRG) as a non-surgical option for repairing exposed skull injuries. In this study, twelve patients who presented to our hospital with scalp defects between September 2018 and March 2022 were included. Patients were evaluated before and three days after treatment using the Visual Analog Scale (VAS) score, inflammatory markers, and topical skin temperature. Additionally, the length of the platelet-rich gel, number of dressing changes, wound-healing time, local scarring, and hair growth were recorded. The average wound area was 17.08 SD5.49 cm2. The platelet-rich gel exhibited a length of 3.09 SD0.09 cm and showed a significant increase in platelet concentration by a factor of 2.43 SD0.07. all 12 patients achieved complete healing, requiring average number of 8.3 SD2.0 dressing changes and resulting in an average wound healing time of 25.0 SD5.8 days. There were no statistically significant differences in the Visual Analog Scale scores, inflammatory markers, or topical skin temperatures before and after treatment. Follow-up assessments conducted 4–10 months after treatment revealed minimal local scars and sparse hair growth. The one-step preparation of platelet-rich gel in reconstructing scalp defects is a simple, safe, and effective non-surgical method. Its advantages include speedy preparation, painless treatment, and small local scars.

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Treatment of scalp defects with a combination of trephination and platelet-rich plasma

Cited by 2 publications

References 7 publications

Platelet-rich gel versus external tissue expansion technique in treating scalp defects: A retrospective study

Platelet-rich gel versus external tissue expansion technique in treating scalp defects: A retrospective study

Application of Platelet-Rich Gel in Repairing Scalp Defects Combined with Skull Exposure: A Case Series Analysis

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