“…In giant-sized keloids, surgical excision is mandatory, reducing tension on the edges of the wound, helping to reduce inflammation in the skin, and specific techniques such as Z-plasty, W-plasty, grafts and flaps can be used, but surgery as monotherapy is not indicated, since it results in high recurrence rates in the range of 45% to 100%, and the combination of other forms of treatment is recommended, such as: continuous pressure after surgery, intralesional corticosteroids, carbon dioxide laser, application of silicone gel, administration of retinoic acid, covering with silicone gel, cryosurgery, use of chemotherapeutic agents (5-fluorouracil), intralesional interferon and radiotherapy [10].…”