Treatment of retinoblastoma by precision megavoltage radiation therapy

Treatment outcome and dose-response relationship in infants younger than 1 year treated for retinoblastoma with primary irradiation

“…This is also the experience reported by Foote et al [6] in which 14/25 (56%) patients required additional treatment following doses between 39 and 51 Gy. They reported that 45 Gy appeared adequate for lesion [18], and even Schipper [9]. This series is unable to document statistical improvement in local control following irradiation alone with doses >36 Gy.…”

Proton Radiotherapy for Childhood Tumors: an Overview of Early Clinical Results

“…There are minimal clinical outcome studies to date on retinoblastoma but a number of centers are starting to generate a critical mass and outcomes will be reported shortly. Chang et al [56] diffuse infiltrating subretinal seeding or extensively advanced tumor, developed multiple recurrences requiring enucleation.…”

Cataract Surgery in Retina Patients

“…Cataract formation is one of the most common ocular complications of external beam radiotherapy for retinoblastoma, which typically occurs in three years following treatment (Schipper et al, 1985;Miller et al 2005). Studies have shown that cataract surgery in patients who have previously received radiation therapy for retinoblastoma is generally not associated with tumor recurrence or spread (Brooks et al, 1990;Portellos and Buckley, 1998).…”