Treatment of recurrent sigmoid volvulus in Parkinson's disease by percutaneous endoscopic colostomy

Toebosch, Susan; Tudyka, Vera; Masclee, Ad; Koek, Ger H.

doi:10.3748/wjg.v18.i40.5812

Cited by 19 publications

(24 citation statements)

References 27 publications

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“…3 Many factors contribute to a patient with PD developing intestinal obstruction. 1,7 Slow intestinal transit, deficient abdominal and diaphragmatic muscular tone, inadequate fluid intake, decreased mobility and autonomic disturbance all contribute to gastrointestinal features. Constipation may result from α-synuclein deposits in the dorsal vagus nucleus and myenteric plexus before involving the substantia nigra, which might explain why gastrointestinal symptoms may occur before the onset Seven cases of sigmoid volvulus in Parkinson's disease aBstract Non-motor features of Parkinson's disease are receiving greater recognition.…”

Section: Discussionmentioning

confidence: 99%

Seven Cases of Sigmoid Volvulus in Parkinson'S Disease

Blackley

Maguire

Daniels

2016

Journal of the Royal College of Physicians of Edinburgh

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Non-motor features of Parkinson's disease are receiving greater recognition. Constipation affects up to 50% of patients with Parkinson's disease and sigmoid volvulus remains an under recognised complication with mortality rates up to 50%. The incidence of sigmoid volvulus in the general population is 1.7/100,000/year. The specific incidence in Parkinson's disease is not known; however, this case series suggests that it is noticeably more than in the general population at 100/100,000/year. This paper highlights the importance of early recognition and treatment of constipation to prevent volvulus developing and thevarious treatments currently available.

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Section: Discussionmentioning

confidence: 99%

Seven Cases of Sigmoid Volvulus in Parkinson'S Disease

Blackley

Maguire

Daniels

2016

Journal of the Royal College of Physicians of Edinburgh

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“…Anismus, the abnormal contraction of the external anal sphincter and puborectalis muscle during attempted defecation, is another problem that can occur in synergy with constipation in approximately 65% of PD patients, which is more frequently observed during “off” periods [16, 28, 47]. Other intestinal complications such as megacolon (mostly asymptomatic), pseudoobstruction, sigmoid volvulus, and bowel perforation may also arise in severe conditions, although their exact incidence is still currently unknown [32, 37, 38, 48]. …”

Section: Gi Manifestations In Autonomic Disordersmentioning

confidence: 99%

Gastrointestinal Dysfunctions in Parkinson’s Disease: Symptoms and Treatments

Poirier

Aubé

Côté

et al. 2016

Parkinson's Disease

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A diagnosis of Parkinson's disease is classically established after the manifestation of motor symptoms such as rigidity, bradykinesia, and tremor. However, a growing body of evidence supports the hypothesis that nonmotor symptoms, especially gastrointestinal dysfunctions, could be considered as early biomarkers since they are ubiquitously found among confirmed patients and occur much earlier than their motor manifestations. According to Braak's hypothesis, the disease is postulated to originate in the intestine and then spread to the brain via the vagus nerve, a phenomenon that would involve other neuronal types than the well-established dopaminergic population. It has therefore been proposed that peripheral nondopaminergic impairments might precede the alteration of dopaminergic neurons in the central nervous system and, ultimately, the emergence of motor symptoms. Considering the growing interest in the gut-brain axis in Parkinson's disease, this review aims at providing a comprehensive picture of the multiple gastrointestinal features of the disease, along with the therapeutic approaches used to reduce their burden. Moreover, we highlight the importance of gastrointestinal symptoms with respect to the patients' responses towards medical treatments and discuss the various possible adverse interactions that can potentially occur, which are still poorly understood.

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“…Hartmann's procedure was performed in 5 (83%) patients and sigmoid resection with primary anastomosis and defunctioning ileostomy in one. The median length of hospital stay was 11 (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24) days. There was only one major complication, a pelvic abscess, which occurred on POD 7 after a Hartmann procedure and required laparotomy ( Table 2).…”

Section: Emergency Surgerymentioning

confidence: 99%