Treatment of radiation-induced hemorrhagic gastritis with endoscopic band ligation

A case report of endoscopic therapy for radiation-induced hemorrhagic gastritis in patient with recurrent hepatocellular carcinoma

“…[2–4] In addition, Kantsevoy et al [10] reported that cryotherapy successfully treated radiation-induced gastritis. Staiano et al [11] also reported that a patient with radiation-induced gastritis who was successfully treated with endoscopic band ligation.…”

Subtotal gastrectomy for diffused hemorrhagic gastritis induced by radiation, following liver resection for hilar cholangiocarcinoma. A case report

“…Acute vasculopathy at the irradiated stomach may progress to obliterative endarteritis, vasculitis and endothelial proliferation, which leads to mucosal ischemia, telangiectasias and ulceration. The mucosa of irradiated stomach seems friable with multiple telangectasias leading to a chronic radiation injury causing bleeding [4] , [5] . The stomach has a thick muscular and mucosal layer and is relatively resistant to radiation.…”

“…The chemotherapy agents that have been reported in such cases are 5-fluorouracil, gemcitabine, mitomycin-C, lomustine (CCNU), paclitaxel and carboplatin, which have been used alone or in combination. In these studies the chemotherapy was given after the completion of radiotherapy or concurrently [4] , [5] , [6] , [7] , [9] , [10] , [11] …”

“…In most cases the treatment of the upper gastrointestinal bleeding is conservative by endoscopic therapy and blood transfusion. Other treatment methods that have been reported for diffused, hemorrhagic gastritis due to radiation are endoscopic band ligation [4] , epsilon-aminocaproic acid (EACA) [5] , hyperbaric oxygen treatment [9] , radiofrequency ablation and argon plasma coagulation. [10] , [11] Recent papers have reported the successful use of oral administered prednisolone for intractable bleeding from hemorrhagic gastritis induced by radiation [12] , [13] .…”

Successful Treatment of Intractable Bleeding Caused by Radiation-Induced Hemorrhagic Gastritis Using Oral Prednisolone: A Case Report

“…Unfortunately, in our patient, the bleeding from antral mucosa was diffuse, and laser coagulation was ineffective. On the other hand, Staiano et al [ 8 ] reported successful treatment of radiation-induced hemorrhagic gastritis using endoscopic band ligation. Because conservative treatment is usually ineffective, gastrointestinal radiation injuries are often treated surgically.…”