Treatment of pyoderma gangrenosum: A multicenter survey‐based study assessing satisfaction and quality of life

Abstract

Pyoderma gangrenosum (PG) lacks consensus regarding treatment, and no prior studies assess treatment satisfaction in PG. The objective of this study was to determine patient-reported satisfaction in the treatment of PG, and associations with satisfaction. Methodology was a multicenter cross-sectional survey for patients who received systemic medication(s) to treat PG. Thirty-five patients completed the survey (mean age: 54.0 years, 65.7% female, response rate: 81.4%). Mean (± SD)

Pyoderma gangrenosum: Readability and quality of online health resources

“…A recent survey of patients with PG found that nearly one-third had an educational level of a high school diploma equivalent or less ( Hobbs et al, 2021 ), highlighting that patients with PG may have difficulty comprehending more than half of the websites in this study. Articles written at a higher grade level were not associated with higher content quality.…”

Pyoderma Gangrenosum of the Breast: A Rare Location of Neutrophilic Dermatoses

“…Oral immunosuppressants are used in severe cases. Prednisolone is used in first line at a dose of 0.5-1mg /kg/day, the other options include: Cyclosporine, Azathioprine, Methtexate and Inflixumab [4] [8][9][10][11][12][13].…”

Crushed Corticosteroid Tablets in Peristomal Pyoderma Gangrenosum

“…1,6 First-line treatment is systemic corticosteroids (oral prednisone 0.5-1 mg/kg per day), especially for progressive, severe, or disfiguring disease. 7 Intralesional steroid therapy is less effective (34%) and, in some instances, may worsen PPG lesions due to the induction of pathergy as a result of injection trauma. 2 Cyclosporine (2.5-5 mg/kg per day) is frequently used as a second-line treatment and may be effective, especially in corticosteroid-resistant cases.…”

“…First-line treatment is systemic corticosteroids (oral prednisone 0.5-1 mg/kg per day), especially for progressive, severe, or disfiguring disease 7. Intralesional steroid therapy is less effective (34%) and, in some instances, may worsen PPG lesions due to the induction of pathergy as a result of injection trauma 2.…”