Treatment of Psoriatic Nail Dystrophy

Abell, E.

doi:10.1111/j.1365-2133.1972.tb01897.x

Cited by 11 publications

(5 citation statements)

References 3 publications

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“…A local penetrating dose of steroid into the digit has been given by needle (5, 8) or by high pressure jet from tools such as porto‐jet (15, 16) or dermojet (17). Needle injection technique may involve a single injection [Gerstein (8)] or multiple injectios [de Berker et al (5)].…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Triamcinolone Acetonide in Various Acquired Nail Dystrophies

Grover

Bansal

Nanda

et al. 2005

The Journal of Dermatology

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The treatment of nail disorders is currently an unsatisfying exercise. Isolated nail involvement generally does not warrant any systemic therapy. At the same time, treatment is requested because of significant cosmetic and functional handicap. Intralesional triamcinolone acetonide (TA) in the proximal nail fold was evaluated as a treatment modality in 30 patients with twenty-nail dystrophy, 14 with nail lichen planus, and 6 with nail psoriasis. The number of involved nails varied from 1-20, and 1-10 nails were treated with TA. Fourteen patients discontinued treatment after 1-2 sittings. Out of the 28 patients completing the treatment protocol, 16 showed 75-100% improvement. Predominant side effects included pain, subungual hematoma formation, proximal nail fold hypopigmentation, and atrophy. TA given as a single injection in the proximal nail fold produced good improvement in a significant number of patients completing the treatment protocol. Lower concentrations of TA (5 mg/ml) were quite effective in treating various dermatoses affecting the nail unit. Our technique had fewer side effects than needle-less injection or multiple injection techniques. Careful attention to injection technique further minimized the side effects associated with the procedure. Sixteen patients completed the six-month follow-up and a relapse of nail changes was seen in 10. The relapses were equally responsive to retreatment. TA injected into the proximal nail fold area is a useful, cheap and efficacious treatment for dermatoses affecting the nail unit.

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Section: Discussionmentioning

confidence: 99%

Efficacy of Triamcinolone Acetonide in Various Acquired Nail Dystrophies

Grover

Bansal

Nanda

et al. 2005

The Journal of Dermatology

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“…It is often found in the bathroom cupboard and it is used as an ordinary face cream 4 . Usually it is prescribed for rosacea 1 . Initially the condition is suppressed, but later the erythema becomes more marked and widespread 3 ' 5 .…”

Section: Discussionmentioning

confidence: 99%

“…However, when application of the cream is discontinued there is a rebound phenomenon. The erythema becoming more marked and studded with sterile papulo‐pastules when the steroid is replaced by a new preparation 4,1 . For these reasons a fluorinated steroid should not be applied to the face except for special reasons e.g., lupus erythematosus.…”

Section: Discussionmentioning

confidence: 99%

Facial Erythema and Telangiectasia with Synalar Cream

Tirlapur

Rice-Oxley

1981

Int J Clinical Practice

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“…Usefulness of intradermal corticosteroids in the treatment of psoriatic nail dystrophies, especially those due to matrix abnormality, has been observed earlier [1,2], but recent reports of Bleeker [4], P eachy et at. [6] and the present study clearly demonstrate that the relapse rates are very high after the treatment is stopped.…”

Section: Commentmentioning

confidence: 99%