Treatment of proliferative sparganosis with mebendazole and praziquantel

High-dose praziquantel therapy for cerebral sparganosis

“…The treatment of choice for cerebral sparganosis is surgical removal because treatment with antihelmintics, including praziquantel, has been described as not effective [1][2][3]. In our patient the clinical improvement, and the normalisation of brain imaging and of anti-sparganum antibody levels suggest that the parasite was eradicated by high dose praziquantel therapy.…”

“…The patient was suspected to have neurocysticercosis and was treated with albendazole Surgical removal of the parasite is the treatment of choice as standard antihelmintic therapy is considered ineffective in sparganosis [1][2][3]. The repeated MRI indicated that the lesion had been wandering again (D and J).…”

A review of human sparganosis in Thailand

“…The patient with pulmonary sparganosis first presented with pulmonary symptoms; a chest X-ray revealed diffuse multiple masses with cavitations, while bronchoscopy with a transbronchial lung biopsy was non-diagnostic. 17 Indeed, there are some reports of pulmonary lesions, described as pulmonary proliferating, [35][36][37][38][39][40][41][42][43][44][45][46][47][48][49] due to intrapulmonary migration of sparganum but finding the worm in the lungs is very rare. With respect to intraosseous sparganosis, the Thai case included here is the first ever reported.…”

Other Cestode Infections

“…There is no known treatment; praziquantel and mebendazole have failed in one case. 37 Intestinal Cestodes: the Tapeworms of Humans…”