Treatment of Post-Stroke Depression

Starkstein, Sergio E.; Hayhow, Brad

doi:10.1007/s11940-019-0570-5

Cited by 61 publications

(38 citation statements)

References 26 publications

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“…Neuromodulation, such as transcranial magnetic stimulation and transcranial direct current stimulation, are promising adjunctive therapies. However, high quality randomized controlled trials using psychotherapy or neuromodulation are limited, and further research is needed[ 57 ].…”

Section: Depressive Disorders After Strokementioning

confidence: 99%

Neuropsychiatric issues after stroke: Clinical significance and therapeutic implications

Zhang¹,

Xu²,

Liu³

et al. 2020

WJP

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A spectrum of neuropsychiatric disorders is a common complication from stroke. Neuropsychiatric disorders after stroke have negative effects on functional recovery, increasing the rate of mortality and disability of stroke survivors. Given the vital significance of maintaining physical and mental health in stroke patients, neuropsychiatric issues after stroke have raised concerns by clinicians and researchers. This mini-review focuses on the most common non-cognitive functional neuropsychiatric disorders seen after stroke, including depressive disorders, anxiety disorders, post-traumatic stress disorder, psychosis, and psychotic disorders. For each condition, the clinical performance, epidemiology, identification of the therapeutic implication, and strategies are reviewed and discussed; the main opinions and perspectives presented here are based on the latest controlled studies, meta-analysis, or updated systematic reviews. In the absence of data from controlled studies, consensus recommendations were provided accordingly.

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Section: Depressive Disorders After Strokementioning

confidence: 99%

Neuropsychiatric issues after stroke: Clinical significance and therapeutic implications

Zhang¹,

Xu²,

Liu³

et al. 2020

WJP

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“…Currently, PSD treatments include antidepressants, psychological therapy, and transcranial magnetic stimulation (TMS). [ 4 ] However, researches have shown that there is no evidence supporting the PSD treatment. [ 18 ] Paroxetine may be an optimal choice for PSD medical treatment, although it has low physiological tolerance and may cause negative side effects.…”

Section: Discussionmentioning

confidence: 99%

“…[ 3 ] In addition, survivors experience different function impairments, while 33% of survivors develop post-stroke depression (PSD). [ 4 ] A research on ischemic stroke patients demonstrated that PSD patients, compared to those having no PSD, had a 15% higher disability rate, were hospitalized for a longer period, and their rehabilitation treatment was less effective than that of non-PSD patients. [ 5 ] Also, PSD has a negative impact on patients' daily living activities (ADLs) and quality of life, and it increases the mortality and suicide rate, thereby, placing a heavy burden on families and the society.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of mirror therapy on upper limb function, activities of daily living, and depression in post-stroke depression patients

Zhang

Liu

et al. 2021

Turk J Phys Med Rehab

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Objectives: This study aims to investigate the effects of mirror therapy (MT) on upper limb function, activities of daily living (ADLs), and depression in post-stroke depression patients. Patients and methods: Between November 2018 and December 2019, a total of 60 post-stroke patients (33 males, 27 females; mean age: 58.45±11.13 years; range, 35 to 88 years) were included. The patients were randomly divided into either the cosntrol group (n=30) or the MT group (n=30). Regular occupational therapy was provided for the control group (two times per day for 30 min per session, five times per week over four weeks). Occupational therapy and MT were used to treat patients in the mirror group (one 30 min session once per day, five times per week over four weeks). Motor function (Fugl-Meyer Assessment of the Upper Extremity, FMA-UE), ADL (Modified Barthel Index, MBI) and depression (17-item Hamilton Depression Scale, HAMD-17) were used to evaluate the treatment outcomes. Results: Before treatment, the mean HAMD-17, FMA-UE, and MBI scores showed no significant difference between the two groups (p>0.05). After treatment, the mirror group exhibited more significant improvements than the control group in terms of the mean HAMD-17, FM-UE, and MBI (p<0.05). After four weeks, the mean FMA-UE and MBI scores revealed more significant improvements than the baseline scores in the control group (p<0.01). The mean HAMD-17, FMA-UE, and MBI scores showed more significant improvements than the baseline scores in the MT group (p<0.001). Conclusion: Based on these results, MT can effectively improve motor function, ADLs, and depression in post-stroke depression patients. The curative effectiveness of MT seems to be more prominent than the regular occupational therapy.

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“…В рамках нескольких исследований получены неоднозначные результаты. Например, при применении миансерина и сертралина не было выявлено достоверной разницы с группой плацебо по частоте и интенсивности возникновения постинсульт ной депрессии [62,68]. В то же время у пациентов, принимавших эсциталопрам, достоверно реже возникала постинсультная депрессия [69].…”

Section: терапия постинсультных аффективных нарушенийunclassified

Anxiety-Depressive Disorders in Patients After Stroke: Prevalence, Approaches to Diagnosis and Therapy

Gogoleva¹,

Vv²

2019

EPh

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Evident anxiety-depressive disorders are being observed in at least one third of patients who have suffered a stroke. They significantly reduce the effectiveness of rehabilitation measures and secondary prevention that is why they require drug and non-drug correction. Anxiety-depressive disorders after a stroke can be caused by a psychological reaction to the disease, damage to the certain areas of the brain, primarily the anterior localization, and exacerbation of pre-stroke mental illness. In the rehabilitation period of stroke in the treatment of anxiety-depressive disorders apart from the classic antidepressants and tranquilizers are proven themselves well neurometabolic drugs with additional positive thymoleptic and anxiolytic effect.

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Treatment of Post-Stroke Depression

Cited by 61 publications

References 26 publications

Neuropsychiatric issues after stroke: Clinical significance and therapeutic implications

Neuropsychiatric issues after stroke: Clinical significance and therapeutic implications

Effectiveness of mirror therapy on upper limb function, activities of daily living, and depression in post-stroke depression patients

Anxiety-Depressive Disorders in Patients After Stroke: Prevalence, Approaches to Diagnosis and Therapy

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