“…Although GERD can induce hiccups via the irritation of the Vagus nerve, long standing hiccups in themselves can cause reduction in the oesophageal motility as well as lowering of oesophageal-gastric sphincter pressure thus favouring GERD [ 1 , 6 ]. Hiccups are classified as temporary (<48 h), persistent (48 h-1 month) or intractable (>1 month), depending on their duration [ 3 ]. Intractable hiccups may cause debilitating problems such as insomnia, anorexia, fatigue, exhaustion, weight loss, depression, opening of surgical wounds, development of hernia and haemorrhoids, inability to undergo imaging such as MRI and even death.…”