Treatment of Peri-Implant Mucositis with Standard of Care and Bioptron Hyperlight Therapy: A Randomized Clinical Trial

Abstract

The aim of this study was to evaluate in a cohort of patients with peri-implant mucositis: (a) the efficacy of professional mechanical debridement therapy assisted using Bioptron Hyperlight Therapy on the reduction in periodontal indexes and (b) the reduction in total oxidative salivary stress. Forty subjects with a diagnosis of peri-implant mucositis were enrolled and randomly assigned to the Study Group (mechanical debridement therapy assisted using Bioptron Hyperlight Therapy) or Control Group (mechanical debridement therapy alone). The study duration was 6 months. Data on plaque index (PI), bleeding on probing (BoP), probing pocket depth (PPD), and pain relief on Visual Analogue Scale (VAS) were recorded at T0, T1 (14 days), T2 (1 month), and T3 (6 months). Group differences were assessed using Student’s t-test and Pearson’s Chi-squared test of homogeneity. PI and PPD decreased in the Study Group at the [T0; T1] time interval and during the overall time of observation significantly more than in the Control Group; BoP and pain on VAS decreased significantly faster in the Study Group than in the Control Group. Differences in Salivary Antioxidant Test (SAT) changes were not significant at any time interval. Patients’ gender and smoking habit were not correlated with the clinical outcomes. Clinical parameters related to peri-implant mucositis significantly improved in the Study Group, which demonstrated the clinical efficacy of the Bioptron Hyperlight Therapy as an adjunct to standard of care for the treatment of peri-implant mucositis. The RCT was registered at the US National Institutes of Health #NCT05307445.

Effect of Ozonated Extra Virgin Olive Oil Gel in The Treatment of Peri-Implant Mucositis: A Retrospective Analysis of 20 Cases

“…The present retrospective clinical study was conducted with the aim of evaluating the clinical effects of the ozonated extra virgin olive oil gel in the treatment of peri-implant mucositis. [14][15][16][17] Specifically, the restitutio ad integrum of the epithelial-connective tissue junction, undermined by bacteria and the inflammation sustained by them, was investigated. This study represents further evidence of the effectiveness of ozonated oil in addition to mechanical decontamination maneuvers.…”

“…In such clinical scenario, treatment of PM is crucial to achieve implant survival through decontamination procedures of implant components and customized at-home and in-office oral hygiene protocols to prevent inflammation of the peri-implant soft tissues [11,12] and to mechanically remove the bacterial biofilm [13][14][15][16]. Evidence-based recommendation support the association a chemical plaque control with the mechanical decontamination of peri-implant sites [17][18][19].…”