Treatment of Palmoplanter Hyperhidrosis by Iontophoresis

Abstract

Twenty-seven patients with idiopathic palmoplanter hyperhidrosis were treated with Iontotherapy over a one year period. In twenty-four cases there was a good response but maintenance therapy was required every 3-4 weeks. MJAFI 2000; 56 : 27-28

Comparison of 10 versus 20 sessions tap water iontophoresis efficacy in the treatment of palmoplantar hyperhidrosis

“…There are also some studies in which TWI sessions have not been performed for a given period of time, rather until a good subjective effect is maintained 12,21 16 performed TWI 1–5 times per week to the patients with palmar HH.…”

“…Several treatment protocols of TWI have been used for palmoplantar HH, while the most effective one is unknown. 11,12,[15][16][17][18][19][20][21][22] Although it is not based on studies comparing the efficacy of different protocols, the recommended and the most commonly used one is 3-4 TWI sessions per week, for a duration of 20-30 min of each session, using a device that delivers 15 to 20 mA of DC. 11,19 With this protocol, the clinical response is achieved after 6-15 sessions over a 2-5 week period.…”

“…On the other hand, the whole treatment period takes a considerable amount of time and requires numerous patient visits, each lasting 20–30 min for almost a month. Nevertheless, the total number of sessions and the number of sessions per week greatly vary among different studies 10–21 . Although TWI is a commonly performed procedure and authors often highlight its benefits over other treatment modalities, the optimal treatment scheme that yields the most valuable result is unclear, and a standardized protocol is currently not available.…”

“…Nevertheless, the total number of sessions and the number of sessions per week greatly vary among different studies. [10][11][12][13][14][15][16][17][18][19][20][21] Although TWI is a commonly performed procedure and authors often highlight its benefits over other treatment modalities, the optimal treatment scheme that yields the most valuable result is unclear, and a standardized protocol is currently not available. Herein, we aimed to compare the efficacy of TWI after 10 and 20 sessions in the treatment of palmoplantar HH and attempted to determine the adequate number of sessions which is required to control the profuse sweating.…”

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“…It is the novel technique used to increase the absorption of drugs across biological tissues such as the skin membrane. 3,4 Electro migration and Electro osmosis is the major principles involved in the iontophoretic drug delivery process. 5 L-Tyrosine is an important amino acid.…”