2017
DOI: 10.1016/j.joms.2017.03.008
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Treatment of Osteomyelitis: A Case for Disruption of the Affected Adjacent Periosteum

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Cited by 10 publications
(4 citation statements)
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“…12 Advanced age exacerbates this condition due to the age related changes in blood supply where the blood supply becomes centripetal (periosteal) rather than centrifugal (endosteal). 13 Diabetes mellitus and anemia was identified in our patient, the former affecting the terminal vasculature and decreasing host resistance and latter causing reduced end oxygen delivery to tissues. This systemic condition along with the anatomical predisposition of mandible with the advanced age predisposed and propagated the condition in our patient.…”
Section: Discussionmentioning
confidence: 71%
See 1 more Smart Citation
“…12 Advanced age exacerbates this condition due to the age related changes in blood supply where the blood supply becomes centripetal (periosteal) rather than centrifugal (endosteal). 13 Diabetes mellitus and anemia was identified in our patient, the former affecting the terminal vasculature and decreasing host resistance and latter causing reduced end oxygen delivery to tissues. This systemic condition along with the anatomical predisposition of mandible with the advanced age predisposed and propagated the condition in our patient.…”
Section: Discussionmentioning
confidence: 71%
“…Mandible is naturally predisposed due to its centrifugal terminal vasculature, corticospongy structure and low mucosal coverage 12 . Advanced age exacerbates this condition due to the age related changes in blood supply where the blood supply becomes centripetal (periosteal) rather than centrifugal (endosteal) 13 . Diabetes mellitus and anemia was identified in our patient, the former affecting the terminal vasculature and decreasing host resistance and latter causing reduced end oxygen delivery to tissues.…”
Section: Discussionmentioning
confidence: 73%
“…et al [35] research the response of mandibular osteomyelitis treated by surgical decortication with disruption of the affected adjacent periosteum in concert with long-term targeted antibiotic therapy. The hypothesis is that, by removing the buccal cortical plate and disrupting the hypertrophically inflamed adjacent periosteum, the medullary bone will be brought in contact with bleeding tissue and circulating immunologic factors and antibiotics, which will promote definitive resolution.…”
Section: Introductionmentioning
confidence: 99%
“…12 Thus, decorticalization and rupture of the affected adjacent periosteum provided an immune-mediated response and accelerated the arrival of the antibiotic, helping with the definitive resolution of the condition and preservation of noble structures. 14 On the contrary, hyperbaric oxygen has also been used as an adjuvant therapy in the treatment of chronic osteomyelitis, especially in recurrent cases. 15 Hyperbaric oxygen therapy increases the pressure of oxygen and the concentration of reactive oxygen species in the blood and tissues.…”
mentioning
confidence: 99%