Treatment of oral leukoplakia with CO2 laser (10,600 nm): analysis of 37 cases

Campos, Wladimir Gushiken de; Esteves, Camilla Vieira; Gallo, Camila de Barros; Domaneschi, Carina; Aranha, Ana Cecília Corrêa; Lemos, Celso Augusto

doi:10.1590/1807-3107bor-2022.vol36.0014

Cited by 6 publications

(6 citation statements)

References 21 publications

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“…Different definitions for recurrence may result in different rates reported in the literature. [ 31 32 33 ] Similar results are shown in studies by Yang et al , and Monteiro et al , some patients treated with laser can recur. Chiesa et al ., concluded in their study that the age of the operated patients and the size of resected lesions are significantly predictive for the development of relapses and new leucoplakia.…”

Section: Discussionsupporting

confidence: 82%

Effectiveness of Diode Laser in Intraoral Soft Tissue Surgeries - An Evaluative Study

Movaniya,

Desai,

Makwana

et al. 2023

Annals of Maxillofacial Surgery

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Introduction: The clinical application of the diode laser seems to have beneficial effects in surgery. The laser provides precise and rapid tissue dissection, excellent haemostasis and lessens post-operative inflammation. This study was done to assess the clinical effectiveness of diode laser in the management of different varieties of intraoral soft-tissue lesions. Materials and Methods: After applying exclusion criteria, a total of 50 samples were selected with benign intraoral soft-tissue lesions treated with a diode laser under local anaesthesia between September 2017 and September 2020. Each patient was followed up on the 3rd, 7th and 15th post-operative days for healing, pain, infection and swelling. Results: From all patients, a total of 50 were evaluated in the study; out of all, 60% of patients had no pain on the 2nd follow-up. As per the Landry Index of Healing, 54% of patients had excellent healing. None of the cases had post-operative bleeding, infection was present in 4% at the 1st–2nd follow-up, and in 2% of cases, post-operative swelling was present. The efficacy of diode lasers was tested using the Chi-square test and P < 0.01, which was statistically significant. Discussion: Diode laser seems to be superior over conventional treatment modalities as it provides a bloodless dry field and increases patient comfort during surgery. It also lessens the post-operative pain and swelling. Diode laser can safely and effectively be used as a treatment modality for benign soft-tissue lesions, without any complication and without compromising the health and function of patients.

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Section: Discussionsupporting

confidence: 82%

Effectiveness of Diode Laser in Intraoral Soft Tissue Surgeries - An Evaluative Study

Movaniya,

Desai,

Makwana

et al. 2023

Annals of Maxillofacial Surgery

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“…25 A research study also identified small bone necrosis at a rate of 8%, delayed wound healing at a rate of 4%, and sclerotic scars at a rate of 4%. 21  Lesion resolution rates were reported in 43.2% 20 and 47.4% 18 of the patients. The disease-free survival rate during the first year was 52.9% in a study.…”

Section: Results Of Individual Studies Oral Potentially Malignant Dis...mentioning

confidence: 92%

“…Oral tumors and OPMDs were found in three studies. [24][25][26] Some studies showed no postoperative complications 20,42,43 ,and one study found no complication in 64.1% of the patients, 18 whereas others claimed the following complications:  Postoperative pain: In a research study, 23 the numerical rating scale (NRS) score declined considerably from 1 month to 1 year. In additional trials, visual analog scale (VAS) ratings varied from 2 to 4, 44 0 after 7 days, 25 1.8 on the first day before declining to 0.03 on day 7, 26 and 6 in 10.4% of the patients.…”

Section: Results Of Individual Studies Oral Potentially Malignant Dis...mentioning

confidence: 99%

“…9,57,58 The CO2 laser alone or in combination with other therapies was beneficial in managing diseases that required minor oral surgery in most included studies. Some studies [18][19][20][21] discovered high recurrence rates following treatment with the CO2 laser. Multiple investigations have also indicated that this therapy has a high recurrence rate.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of the Effectiveness of the Carbon Dioxide (CO2) Laser in Minor Oral Surgery: A Systematic Review

Asnaashari,

Behnam Roudsari,

Shirmardi

2023

J Lasers Med Sci

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Introduction: Lasers in oral surgery have been extensively studied in recent years. Laser treatment is now a well-known technology that is frequently employed on oral soft tissues. The carbon dioxide (CO2) laser was one of the first soft tissue removal lasers. Because of the strong affinity of the CO2 laser to water, it is best used for removing, vaporizing, and coagulating these tissues. In minor oral surgery, CO2 laser therapy has shown advantages. Therefore, this study examined the CO2 laser use in minor oral soft tissue surgery. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards were followed in this study. A question for research encompassing the inclusion criteria for the participants, intervention, comparison, outcome, and study design (PICOS) was formulated. The search queries were entered into the PubMed/Medline, Scopus, and Embase databases. Consideration was given to publications published between January 1, 2018 and March 15, 2023. Results: The research included 37 studies after narrowing search results, eliminating duplicate titles, and conducting an eligibility review (three animal studies, seven case reports, three case series, and twenty-four clinical studies). CO2 lasers alone or in combination with other therapies successfully treated oral potentially malignant disorders (OPMDs), oral tumors, oral fibrous-epithelial lesions, gingival melanin hyperpigmentation, pyogenic granuloma, socket preservation, mucocele, high labial frenulum attachment, and so on. CO2 lasers reduced intra- and postoperative complications and adverse effects, improved postoperative functional results, ablated tissues with precision, and minimized disease recurrence and malignant transformation. Conclusion: Our study found that the CO2 laser in oral minor surgeries is successful, but further randomized clinical trials and multicenter studies are recommended to compare CO2 laser surgery to other treatments.

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“…Previous studied have reported good post-operative healing with no complications in case of laser resection of leukoplakia. [2][3][4][5][6] Wladimir Gushiken de 7 in their reported analysis of 37 cases of laser excision of leukoplakia, reported that in 13/37 patients, leukoplakia recurred; and 8/37 patients, a malignant transformation occurred. Frame et al have reasoned that the new epithelium formed after laser application which migrates from the periphery to cover the wound may originate from an area of potentially unstable mucosa thereby explaining the recurrence.…”

Section: Discussionmentioning

confidence: 99%

Managing leukoplakia with diode laser: A report of two cases

Bacholkar

Navalkar²

2023

IJOHD

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Oral leukoplakia is the most common precancerous lesion of the oral mucosa. WHO defined it as a lesion which has a white patch or plaque on the oral mucosa that cannot be removed by scraping and cannot be classified clinically or microscopically as another disease process. Management of oral leukoplakia should begin with elimination of predisposing habit. There are currently different approaches in the management of Leukoplakia such as scalpel surgery, systemic carotenoids and antioxidants, electro cauterization, cryotherapy and Lasers. Even though on-surgical options are preferred choice of treatment, it takes time to achieve complete regression of lesion and sometimes may not achieve complete resolution. On the other hand, conventional surgical techniques are invasive and cause trauma to the patient. Excision of precancerous oral lesions using LASER offers comparative advantages over traditional scalpel excision. Laser is an acronym for Light Amplification by stimulated emission of radiation. It is surgical technique which excises the targeted tissue using emission of a monochromatic light of specific wavelength. Because of this property, laser excision of the tissue results in complete bloodless field of surgery, reduced chances of post-surgical inflammation and infections and hence better treatment compliance of the patients towards the surgery. This is one of the important goals for management of oral potentially malignant disorders. We present two case reports of homogeneous leukoplakia treated using diode lasers of wavelength 810nm with follow-up. Both cases did not report any post-operative discomfort or inflammation. The aim of this case report is to highlight the importance of laser excision with minimal complications and better treatment outcomes.

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Treatment of oral leukoplakia with CO2 laser (10,600 nm): analysis of 37 cases

Abstract: Camilla Vieira ESTEVES (a) Camila de Barros GALLO (a) Carina DOMANESCHI (a)

Cited by 6 publications

References 21 publications

Effectiveness of Diode Laser in Intraoral Soft Tissue Surgeries - An Evaluative Study

Effectiveness of Diode Laser in Intraoral Soft Tissue Surgeries - An Evaluative Study

Evaluation of the Effectiveness of the Carbon Dioxide (CO2) Laser in Minor Oral Surgery: A Systematic Review

Managing leukoplakia with diode laser: A report of two cases

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