Treatment of multiple intracutaneous cornifying epitheliomata using isotretinoin

Henfrey, Julie I.

doi:10.1111/j.1748-5827.1991.tb00952.x

Cited by 4 publications

(2 citation statements)

References 5 publications

(2 reference statements)

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“…Isotretinoin has been successfully used for the pharmacological therapy of multiple benign cutaneous adnexal tumours, such as multiple intracutaneous cornifying epitheliomas (keratoacanthomas, ICE), 15,18,21 inverted papilloma, 18 sebaceous adenomas 18,22 and epidermal cysts 18 . For this reason, isotretinoin was chosen as pharmacological therapy of multiple benign pilomatrixomas.…”

Section: Discussionmentioning

confidence: 99%

Isotretinoin in the treatment of multiple benign pilomatrixomas in a mixed‐breed dog

Toma¹,

Noli²

2005

Veterinary Dermatology

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An 18-month-old cross-breed dog developed multiple skin nodules, which over 8 months had increased in size and number. Biopsy samples were submitted for histopathological examination and revealed multiple benign pilomatrixomas. The dog was treated with 1 mg kg(-1) isotretinoin daily, which led to a stabilization of the size and number of the lesions. Attempts to lower the dosage to an every other day regimen led to an increase in the nodules' size and number. Monthly complete blood count and chemistry tests and Schirmer tear tests were performed to monitor any adverse effects of the retinoid treatment. No adverse effects were noted. To the authors' knowledge, this is the first report of multiple pilomatrixomas arising in a young dog and successfully controlled with oral retinoids.

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Section: Discussionmentioning

confidence: 99%

Isotretinoin in the treatment of multiple benign pilomatrixomas in a mixed‐breed dog

Toma¹,

Noli²

2005

Veterinary Dermatology

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“…In dogs that are prone to developing multiple tumours surgical management may not be appropriate and further lesions are likely. Successful treatment of multiple intracutaneous cornifying epitheliomata using isotretinoin has been reported (Henfrey 1991).…”

Section: Behaviour/treatment/prognosismentioning

confidence: 99%

Urinary Tract

2001

Small Animal Oncology

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and the Radiology Department, Queens Veterinary School Hospital, Cambridge, for contributing many of the pictures used to illustrate the text. We should also acknowledge the artistic skills of John Fuller who was responsible for the original line drawings reproduced in this book.We are also grateful to Dr Davina Anderson for her help in reading the text and advice on surgical matters, Malcolm Brearley for his help with Chapter 13, Nervous System, Dr David Williams, Chapter 16, on the eye, and Mike Herrtage, Chapter 14, Endocrine System. Herpesvirus family Burkitt's lymphoma in Africa, Man (Epstein-Barr virus) Nasopharyngeal carcinoma in China HHV-8 Kaposi's sarcoma Man Mareks disease virus Mareks disease/lymphoma Chicken Papovavirus family Papillomas/warts Man and animals (papilloma viruses) Carcinomas of cervix Man ?Bowen's disease/squamous cell Cat carcinoma Adenovirus family Adenomas Sheep RNA viruses Retrovirus family HTLV-1 Adult T cell leukaemia/lymphoma Man FeLV Leukaemia/lymphoma Cat BLV Bovine leukosis/lymphoma Cow ALV Avian leukosis/lymphoma Chicken

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Skin

2001

Small Animal Oncology

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Treatment of multiple intracutaneous cornifying epitheliomata using isotretinoin

Cited by 4 publications

References 5 publications

Isotretinoin in the treatment of multiple benign pilomatrixomas in a mixed‐breed dog

Isotretinoin in the treatment of multiple benign pilomatrixomas in a mixed‐breed dog

Urinary Tract

Skin

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