Treatment of Multiple Apocrine Hidrocystomas With Trichloroacetic Acid

Abstract

The apocrine hidrocystoma is a benign adenomatous cystic proliferation derived from apocrine glands, which frequently occurs in periocular tissues. These cystadenomas may occur bilaterally, in multiple disfiguring confluent groups on both the upper and lower lids. Although these lesions have been treated successfully with meticulous surgical extirpation and electrosurgery, this report describes the successful treatment of two patients, each with multiple large (>7 mm) periocular apocrine hidrocystomas by either chemical ablation of the cystic epithelium with trichloroacetic acid (TCA) or surgical excision. Examination of the cysts at 1, 3, and 6 months after TCA treatment revealed well-healed lesions without cyst recurrence. Most of the TCA-treated cysts resolved completely, without leaving any trace to clinical examination. Treatment of cysts with TCA was technically simpler and much less time-consuming than surgical excision. The treatment of large apocrine hidrocystomas with TCA is an effective and expeditious method of treating these disfiguring and recalcitrant lesions.

Management of malignant and benign eyelid lesions

“…Marsupialization of the cyst is curative and recurrence is rare. A nonsurgical option reported by Dailey et al [5] consists of intralesional injection of trichloroacetic acid, especially useful for large or confluent lesions.…”

Giant Hidrocystoma of the Orbit Presenting with Inversion and Ptosis of the Upper Eyelid

“…Medical treatment of multiple, smaller periocular lesions has been advocated by laser thermo-ablation and, more recently, trichloroacetic acid chemical ablation. 4 As the hidrocystoma in our case was oversized and caused additional eyelid and ocular surface problems, we chose to perform total excision.…”

Giant eccrine hidrocystoma presenting with unilateral ptosis and epiphora

“…Medical treatment of multiple, smaller periocular lesions has been advocated by laser thermo-ablation and, more recently, trichloroacetic acid chemical ablation [6].…”