Treatment of Multifocal Cutaneous Squamous Cell Carcinoma with Strontium-90 and Cryotherapy in a Midland Painted Turtle (Chrysemys picta marginata)

Ferris, Rachel L.; Quesenberry, Katherine E.

doi:10.5818/18-12-174.1

Cited by 2 publications

(1 citation statement)

References 26 publications

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“…In reptiles, SCC typically arises from the skin 4 5 6 , including the eyelids 7 8 , but also can originate from the oral cavity 4 6 9 10 11 , including the tongue 12 , the cloaca and surrounding structures 1 , and, less frequently, the ear canal of a leopard gecko ( Eublepharis macularius ) 13 or the rattle of a rattlesnake ( Crotalus adamanteus ) 14 . In chelonians, SCC has been described in different turtle and tortoise species 13 15 16 17 18 19 20 . Metastases have only been described in turtles, affecting the inner organs (lungs, liver, kidneys, heart, spleen) and skeletal muscle 11 16 .…”

Section: Introductionmentioning

confidence: 99%

Metastasizing squamous cell carcinoma in a 50-year-old Eastern Hermann‘s tortoise (Testudo hermannii boettgeri)

Müller,

Erokhina,

Gletscher

et al. 2023

Tierarztl Prax Ausg K Kleintiere Heimtiere

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A 50-year-old female Hermann’s tortoise (Testudo hermannii boettgeri) was presented with anorexia and lethargy. Clinical examination revealed multiple, visually inconspicuous but indentable areas in the shell corresponding to osteolysis radiographically. Soft tissue nodules and osteolytic lesions were also noted in the limbs. Laboratory results revealed elevated aspartate aminotransferase activity and uric acid concentrations, hypoglycemia, and hyperphosphatemia. Klebsiella oxytoca was isolated from a biopsied scutal area, and the biopsy suggested neoplasia. After a short period of clinical improvement, the animal's condition deteriorated, and it died. Post mortem computed tomography revealed polyostotic lytic lesions of multiple bones and the shell with associated soft tissue nodules protruding into the coelom, and nodular lung lesions. Necropsy, histopathology, and immunohistochemistry secured a diagnosis of a poorly differentiated, pan-cytokeratin-positive squamous cell carcinoma with widespread soft tissue and bone metastases, osteolysis and desmoplasia.

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