Treatment of multifocal atrial tachycardia with metoprolol

Hazard, Patrick B.; Burnett, Charles R.

doi:10.1097/00003246-198701000-00004

Cited by 34 publications

(4 citation statements)

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“…However, the research have shown, that metoprolol appears to be more effective than verapamil in treating multifocal atrial tachycardia ( Arsura et al, 1988 ). In long-term treatment selective β-blockers should be considered in patients with a recurrent and symptomatic multifocal AT ( Hazard and Burnett, 1987 ). In case of hemodynamically stable patients with macro-reentrant atrial tachycardia (MRAT) intravenous administration of β-blockers should be taken into consideration in acute management to control and decrease the ventricular rhythm.…”

Section: Practical Aspects Of β-Blockers Therapy In Treatment Of Card...mentioning

confidence: 99%

Beta-blockers in cardiac arrhythmias–Clinical pharmacologist’s point of view

et al. 2023

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β-blockers is a vast group of antiarrhythmic drugs which differ in their pharmacokinetic and chemical properties. Some of them block β-adrenergic receptors selectively while the others work non-selectively. Consequently, they reduce the influence of the sympathetic nervous system on the heart, acting negatively inotropic, chronotropic, bathmotropic and dromotropic. Although they have been present in medicine since the beginning of the 1960s, they still play a crucial role in the treatment of cardiac arrhythmias. They are also first-line group of drugs used to control the ventricular rate in patients with the most common arrhythmia–atrial fibrillation. Previous reports indicate that infection with SARS-CoV-2 virus may constitute an additional risk factor for arrhythmia. Due to the aging of the population in developed countries and the increase in the number of patients with cardiac burden, the number of people suffering from cardiac arrhythmias will increase in the upcoming years. As a result the role of above-mentioned beta-blockers will remain significant. Particularly noteworthy is propranolol–the oldest beta adrenergic antagonist, which in recent years has found additional applications due to its unique properties. In this article, we reviewed the accessible literature and summarized the current guidelines on the use of beta-blockers in the treatment of cardiac arrhythmias.

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Section: Practical Aspects Of β-Blockers Therapy In Treatment Of Card...mentioning

confidence: 99%

Beta-blockers in cardiac arrhythmias–Clinical pharmacologist’s point of view

et al. 2023

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“…Лечение МОПРТ антиаритмическими препаратами представляет значительные трудности. Современные рекомендации указывают на то, что, как и ранее, наибольшую клиническую доказательную базу в купировании, профилактике или урежении частоты желудочковых сокращений имеют бета-адреноблокаторы (отмечается эффективность метопролола) и недигидропиридиновые антагонисты кальция (верапамил, дилтиазем) [2,5,22]. Есть данные о положительном влиянии на течение аритмии амиодарона и антиаритмиков IC класса (пропафенон, флекаинид) как у взрослых, так и детей [23].…”

Section: многоочаговая предсердная тахикардияunclassified

Atrial Tachyarrhythmias and Atrial Flutter: the Basics of Diagnostics and Modern Opportunities of Therapy

Bunin

Miklishanskaya

Zolozova

et al. 2019

Racionalʹnaâ farmakoterapiâ v kardiologii

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The article is devoted to the description of all types of atrial tachyarrhythmias, including inappropriate sinus tachycardia, which, as a rule, is not paid enough attention in the domestic literature, sinoatrial node reentrant tachycardia, focal and multifocal atrial tachycardia, atrial flutter, and atrial fibrillation. The electrophysiological mechanisms of development and electrocardiographic criteria for the diagnosis of these cardiac rhythm disturbances are presented. Along with this, the article discusses the modern view of the strategy and tactics of pharmacological cardioversion and preventive therapy in patients with the main types of atrial tachyarrhythmias and atrial flutter. It is noted that the prognosis for inappropriate sinus tachycardia, as a rule, is favorable, and therefore, aim of treatment is to reduce the symptoms, and in their absence medical treatment is not necessary. Much attention is paid to drug and interventional treatment of atrial flutter. It is emphasized that catheter ablation of isthmus-dependent atrial flutter in most cases is preferred over long-term pharmacotherapy. However, in prolonged observation (more than 3 years), nearly 1/3 of patients may develop paroxysmal atrial fibrillation. At the same time, catheter ablation of atypical atrial flutter is, in most cases, substantially less effective. The indications and side effects of catheter ablation of the sinus node are also discussed. The authors provide a critical analysis of traditional approaches to the treatment of atrial tachyarrhythmias and analyze new recommendations for the management of these patients presented in Europe and the USA. Based on these recommendations, clear algorithms for the management of patients with atrial tachyarrhythmias are given. The need to prevent thromboembolic complications in some types of atrial tachyarrhythmias is emphasized.

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“…Weiterhin überdurch-schnittlich wurden Diabetes mellitus (in ca. 25% der Fälle) [22,27] und koronare Herzerkrankungen, Herzinsuffizienz und Klappenerkrankungen beobachtet, die mit einer linksatrialen Belastung einhergehen können. Bei einem Teil der erwachsenen Patienten wurde auch eine Digitalistoxizität vermutet.…”

Section: äTiologie Bei Erwachsenenunclassified

“…und anderen β-Blockern[4,22,24,41] zahlreiche andere Antiarrythmika in unterschiedlichen Kombinationen eingesetzt[23,25,28,38,42,51]. Eine spezielle Therapiestrategie, welche einen sicher positiven Effekt auf die MAT zeigte, ließ sich jedoch auch damit nicht eindeutig nachweisen.…”

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