Treatment of Motor and Sensory Detrusor Instability by Electrical Stimulation

Abstract

A new application of electrical stimulation to inhibit detrusor activity has been used in 15 patients with a variety of neural lesions. The results were astonishingly good and the device was well tolerated. In patients treated successfully for detrusor instability an absence of urgency occurred as a by-product of electrical stimulation. Therefore, stimulation was used to treat uncomfortable bladder urgency without detrusor instability and was successful in the majority of patients.

Role of percutaneous posterior tibial nerve stimulation either alone or combined with an anticholinergic agent in treating patients with overactive bladder

“…For the first time in 1983, McGuire et al [11] described electrical stimulation of the tibial nerve in a mixed group of patients with detrusor instability, multiple sclerosis, spinal cord injury, and interstitial cystitis. After treatment, 55% of patients were dry, and 32% of them had improvement.…”

Acupuncture in the treatment of psychogenic erectile dysfunction: first results of a prospective randomized placebo-controlled study

“…17,18 In urologic disorders, acupuncture has been successful both as primary or adjuvant therapy in enuresis, bladder instability and male infertility. [4][5][6][19][20][21][22][23] To our knowledge, only three papers on the use of acupuncture in erectile dysfunction have been presented in the international, peer-reviewed literature. [8][9][10] In addition, our study represents the first attempt to conduct a randomized, prospective trial, where acupuncture is tested against a valid placebo treatment.…”

“…In median, the number of treatment sessions was 6.2 (range 4-10) and 11 (range [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] in the placebo group and in the treatment group, respectively. We could not observe any side effects according to acupuncture therapy.…”

Neuromodulation in Management of Overactive Bladder

“…During experimental studies in nonhuman primates with spinal cord injury to improve bipolar anal sphincter Stimulation, McGuire et al found that detrusor activity inhibition was equally achieved by applying a positive current to the anal sphincter with a negative electrode placed over the posterior tibial nerve (McGuire et al, 1983). Similar results were obtained by applying current on the common peroneal or posterior tibial nerve and a ground electrode placed over the same nerves contralaterally.…”

“…Similar results were obtained by applying current on the common peroneal or posterior tibial nerve and a ground electrode placed over the same nerves contralaterally. The idea of stimulating tibial nerve was based on the traditional Chinese practice of using acupuncture points to inhibit bladder activity (McGuire et al, 1983). Transcutaneous posterior tibial nerve stimulation was then evaluated in clinical trials with variable results.…”