Treatment of moist desquamation for patients undergoing radiotherapy

Suresh, Raagini; Raffi, Jodie; Yuen, Florence; Murase, Jenny E.

doi:10.1016/j.ijwd.2018.12.002

Cited by 7 publications

(6 citation statements)

References 4 publications

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“…Treatment of more severe reactions, such as moist desquamation, should help prevent secondary infection and promote wound healing. Experts recommend cleansing the site with 0.5% chlorhexidine solution 96 followed by debridement and application of moist dressings over de‐epithelialized skin 74,97,98 . Wound reexamination, cleansing, and dressing changes should occur every 24–48 hours 96 .…”

Section: Complications Of Radiation Therapymentioning

confidence: 99%

“…Experts recommend cleansing the site with 0.5% chlorhexidine solution 96 followed by debridement and application of moist dressings over de‐epithelialized skin 74,97,98 . Wound reexamination, cleansing, and dressing changes should occur every 24–48 hours 96 . Some experts avoid petroleum jelly and standard gauze, instead favoring a hydrophilic silver ion dressing covered by a nonstick silicone dressing 96 .…”

Section: Complications Of Radiation Therapymentioning

confidence: 99%

“…Wound reexamination, cleansing, and dressing changes should occur every 24–48 hours 96 . Some experts avoid petroleum jelly and standard gauze, instead favoring a hydrophilic silver ion dressing covered by a nonstick silicone dressing 96 . Healing usually occurs over 3–4 days, but wound care should continue until complete re‐epithelization, which can take up to 3 weeks 96 .…”

Section: Complications Of Radiation Therapymentioning

confidence: 99%

“…Some experts avoid petroleum jelly and standard gauze, instead favoring a hydrophilic silver ion dressing covered by a nonstick silicone dressing 96 . Healing usually occurs over 3–4 days, but wound care should continue until complete re‐epithelization, which can take up to 3 weeks 96 . If signs of infection develop, wounds and discharge should be cultured and empiric antibiotics should be started 80 .…”

Section: Complications Of Radiation Therapymentioning

confidence: 99%

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Dermatologic sequelae of breast cancer: From disease, surgery, and radiation

2020

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The care of breast cancer patients is important to dermatologists. Breast cancer’s initial presentation, clinical progression, and its associated treatments can result in a variety of cutaneous complications. Dermatologists may be the first to identify a breast cancer diagnosis, as a subset of patients first present with direct extension of an underlying tumor or with a cutaneous metastasis. The surgical treatment of breast cancer also begets a variety of skin sequelae, including postoperative lymphedema, soft tissue infections, seromas, pyoderma gangrenosum, and scarring disorders. Moreover, breast cancer radiation treatment commonly results in skin changes, which can range from mild and temporary dermatoses to chronic and disfiguring skin ulceration, fibrosis, and necrosis. Radiation may also precipitate secondary malignancies, such as angiosarcoma, as well as rarer dermatologic diseases, such as radiation‐induced morphea, lichen planus, and postirradiation pseudosclerodermatous panniculitis. Finally, breast cancer is also associated with an array of paraneoplastic phenomena, including Sweet’s syndrome and the rarer intralymphatic histiocytosis. Herein, we review the dermatological manifestations of breast cancer, including conditions associated with its presentation, progression, and treatment sequelae. Chemotherapy‐induced cutaneous side effects are beyond the scope of this review. This article provides a comprehensive review for dermatologist to be able to identify, diagnose, and manage breast cancer patients from initial presentation to treatment monitoring and subsequent follow‐up.

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Section: Complications Of Radiation Therapymentioning

confidence: 99%

Section: Complications Of Radiation Therapymentioning

confidence: 99%

Section: Complications Of Radiation Therapymentioning

confidence: 99%

Section: Complications Of Radiation Therapymentioning

confidence: 99%

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Dermatologic sequelae of breast cancer: From disease, surgery, and radiation

2020

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“…3 More severe clinical manifestations such as moist desquamation occur in approximately 36% of the patients who undergo radiotherapy. 4 …”

Section: Introductionmentioning

confidence: 99%

Use of Chamomile Infusion to Mitigate Radiotherapy-Induced Dry Desquamation in Head and Neck Cancer Patients

et al. 2022

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Purpose: To evaluate the effect of using a compress with Chamomilla recutita infusion in the regression of dry desquamation and in the prevention of moist desquamation in head and neck cancer patients undergoing radiotherapy. Methods: A prospective intervention study was carried out from May 2019 to May 2021. In total, 43 participants were included, who were instructed to apply the compress with the infusion 3 times a day, after occurrence of dry desquamation. Skin evaluation took place daily from initiation of the intervention up to the end of radiotherapy. Results: All the participants presented dry desquamation regression, where 65.1% (95% CI 50.1-78.1) had total regression until the end of radiotherapy, with a mean of 9 days of regression. Only 34.9% (95% CI 21.8-49.9) of the participants developed moist desquamation by the end of the radiotherapy sessions, with a mean accumulated dose of ionizing radiation of 50.9 Gy. Conclusion: This study highlighted the potential clinical benefits of using Chamomilla recutita in the regression of dry desquamation and in the prevention of moist desquamation.

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