Treatment of mild to moderate dehydration in children with oral rehydration therapy

Diggins, Kristene

doi:10.1111/j.1745-7599.2008.00338.x

Cited by 5 publications

(3 citation statements)

References 8 publications

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“…Those with severe dehydration will benefit from early initiation of intravenous fluids, whereas those with mild to moderate dehydration can be successfully treated with oral rehydration therapy and those without any dehydration require no medical intervention at all, leading to shorter hospital stays and outpatient treatment. 29,30 Thus, underestimating or overestimating the severity of dehydration can lead to adverse outcomes for patients either in the form of inadequate resuscitation or unnecessarily invasive and costly interventions, respectively.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Standard and Mobile Health–Supported Clinical Diagnostic Tools for Assessing Dehydration in Patients with Diarrhea in Rural Bangladesh

Bilal

Nelson

Meisner

et al. 2018

The American Journal of Tropical Medicine and Hygiene

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Diarrhea remains a leading cause of morbidity and mortality in patients worldwide. The objective of this study was to determine the relative inter-rater reliability and usability of standard and Mobile health (mHealth)-supported World Health Organization (WHO) algorithms for dehydration assessment in patients with acute diarrhea in a rural, low-income country hospital. Two nurses blinded to each other's examinations assessed dehydration status on patients soon after hospital arrival using either the standard WHO algorithm printed on a laminated card or an mHealth-supported WHO algorithm downloaded onto a smartphone. The assignment of assessment tool was based on odd or even enrollment date. The inter-rater reliability for dehydration assessment between the two nurses was calculated using Cohen's K statistic for each study group. A total of 496 patients (< 5 years = 349,> 5 years = 147) were enrolled in the study; 132 (27%) had some or severe dehydration, and 364 (73%) had no dehydration on arrival. Cohen's K statistic demonstrated greater reliability for the mHealth-supported dehydration assessment (0.59) compared with the standard assessment (0.50) in the overall population ( < 0.0001), as well as in the pediatric (0.43 versus 0.37, < 0.0001) and adult (0.79 versus 0.57, < 0.0001) populations individually. This is the first study to show that mHealth can improve the reliability of nursing dehydration assessment in patients with acute diarrhea and the first to report on the reliability of the WHO algorithm in adult patients specifically. Future studies should focus on the impact of mHealth-supported dehydration assessment on patient-centered outcomes and examine its reliability in different settings worldwide.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Standard and Mobile Health–Supported Clinical Diagnostic Tools for Assessing Dehydration in Patients with Diarrhea in Rural Bangladesh

Bilal

Nelson

Meisner

et al. 2018

The American Journal of Tropical Medicine and Hygiene

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“…The increase in permeability of the intestinal mucosal barrier, called leaky gut syndrome, often occurs in the course of inflammatory bowel disease [ 22 ]. It has been proven that, contrary to widespread opinion, oral administration of fluids to patients not only protects from fluid loss, but allows for reduction in the volume of infusion [ 23 ].…”

Section: Intestinal Mucosal Barriermentioning

confidence: 99%

Enteral feeding and its impact on the gut immune system and intestinal mucosal barrier

Szefel¹,

Kruszewski²,

Buczek³

2015

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Enteral feeding is the preferred method of nutritional therapy. Mucosal lack of contact with nutrients leads do lymphoid tissue atrophy, immune system functional decline, and intensification in bacterial translocation. Currently, it is assumed that microbiome is one of the body organs that has a significant impact on health. The composition of microbiome is not affected by age, sex, or place of residence, although it changes rapidly after diet modification. The composition of the microbiome is determined by enterotype, which is specific for each organism. It has a significant impact on the risk of diabetes, cancer, atherosclerosis, and other diseases. This review gathers data on interaction between gut-associated lymphoid tissue, mucosa-associated lymphoid tissue, microbiome, and the intestinal mucosal barrier. Usually, the information on the aforementioned is scattered in specialist-subject magazines such as gastroenterology, microbiology, genetics, biochemistry, and others.

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“…The World Health Organization advise fluid and electrolytes replacement as the therapy of choice for treatment of dehydration 2. However, although the mortality rate is decreased by rehydration,3 the duration and number of diarrhoea episodes are not affected 4.…”

Section: Introductionmentioning

confidence: 99%

LactobacillusacidophilusandBifidobacteriumbifidumstored at ambient temperature are effective in the treatment of acute diarrhoea

Rerksuppaphol

2010

Annals of Tropical Paediatrics

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IntroductionProbiotics have demonstrated potential to reduce duration of diarrhoea and frequency of watery stools. Probiotics such as Lactobacillus acidophilus and Bifidobacterium bifidum (Infloran®) are usually maintained at a storage temperature of 4°C which is generally not feasible in tropical or sub-tropical countries.AimThe efficacy of Infloran® for treatment of acute diarrhoea when stored at 28–32°C (room temperature) was evaluated.Methods This was a double-blind, randomised study of infants and children aged 2 months to 7 years with acute diarrhoea. Patients were randomly assigned to receive Infloran® stored at 4°C, at room temperature, or to a placebo group. Duration of diarrhoea was a primary outcome, while the number of stools, hospital stay and requirement for rehydration fluid were secondary outcomes.ResultsProbiotics shortened duration of diarrhoea (34.1 and 34.8 hrs when stored either at 4°C or at room temperature, respectively, and 58 hrs with placebo, p<0.01) and reduced the number of stools (7.3 and 8 vs 15.9 with placebo, p<0.01).Conclusion Administration of probiotics is beneficial as additional treatment of acute diarrhoea and efficacy is not affected by storage temperature.

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Treatment of mild to moderate dehydration in children with oral rehydration therapy

Cited by 5 publications

References 8 publications

Evaluation of Standard and Mobile Health–Supported Clinical Diagnostic Tools for Assessing Dehydration in Patients with Diarrhea in Rural Bangladesh

Evaluation of Standard and Mobile Health–Supported Clinical Diagnostic Tools for Assessing Dehydration in Patients with Diarrhea in Rural Bangladesh

Enteral feeding and its impact on the gut immune system and intestinal mucosal barrier

LactobacillusacidophilusandBifidobacteriumbifidumstored at ambient temperature are effective in the treatment of acute diarrhoea

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