Treatment of Melasma Using Fractional Photothermolysis: A Report of Eight Cases with Long-Term Follow-Up

Katz, Tracy M.; Glaich, Adrienne S.; Goldberg, Leonard Harry; Firoz, Bahar F.; Dai, Tianhong; Friedman, Paul M.

doi:10.1111/j.1524-4725.2010.01621.x

Cited by 48 publications

(55 citation statements)

References 42 publications

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“…Greater depths of penetration can be achieved using fractional laser as entire skin surface is not ablated. Hence, dermal melasma can be targeted [8,9].…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Lasers on Pigmentary Lesions

Voyatzi¹

2017

Pigmentary Disorders

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Our purpose is to study the efficacy of the alexandrite laser (755 nm) and the fractional laser when treating pigmentary lesions .We use the data of our private office of the last five years (2011)(2012)(2013)(2014)(2015) We treated 1000 patients with freckles with alexandrite laser, 200 patients with melasma with fractional laser, 100 patients with post inflammatory hyperpigmentation with alexandrite laser and 60 patients with post inflammatory hyperpigmentation with fractional laser. We also studied the side effects of the therapies. Alexandrite laser has excellent results for freckles, while the combination of chemical peelings and fractional laser is good for the treatment of melasma. Post inflammatory hyperpigmentation has an intermediate response. The recurrence rates are higher in melasma and the side effects are generally minimal.

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“…Greater depths of penetration can be achieved using fractional laser as entire skin surface is not ablated. Hence, dermal melasma can be targeted [8,9].…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Lasers on Pigmentary Lesions

Voyatzi¹

2017

Pigmentary Disorders

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“…Their efficacy for different clinical tasks had been demonstrated in a number of studies [65][66][67][68][69]. Non-ablative FP is an effective method of smoothing wrinkles, skin lifting (tightening), general enhancement of the state of the skin, and in the treatment of pigmentation disorders and atrophic scars.…”

Section: Reviewsmentioning

confidence: 99%

Fractional Laser Photothermolysis in the Treatment of Skin Defects: Possibilities and Effectiveness (Review)

Karabut¹,

Gladkova²,

Feldchtein³

2016

Sovrem Tehnol Med

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Nizhny Novgorod State Medical Academy, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russian Federation For skin defect treatment and rejuvenation the ablative laser skin resurfacing with a CO 2 laser is widely applied in cosmetology and dermatology. However this treatment can result in the risk of undesirable side effects and requires a long-term recovery after the procedure. When non-ablative laser skin rejuvenation is used as an alternative, the level of safety is increased, however the efficacy of the procedure is considerably reduced.The use of fractional laser photothermolysis is a particularly important step in the development of laser technology for cosmetology and dermatology. Due to the creation of only microscopic areas of thermal damage under the laser exposure, this method results in safe, quick healing and complete recovery of the skin without any undesirable side effects. The review presented here illustrate the high efficacy of the application of both ablative and non-ablative fractional laser photothermolysis for wrinkles reduction, for general improvement of the skin appearance, for the abnormal pigmentation treatment, and the removal or appearance improvement of atrophic scars from acne as well as in areas of skin stretching (striae).Key words: laser technologies in cosmetology; ablative and non-ablative laser exposure; fractional laser photothermolysis.For contacts: Maria M. Karabut,

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“…Fractional Non-Ablative Laser: Controversy about the use of fractional erbium glass laser (1550 nm) in melasma has emerged from vast publications [80][81][82][83][84][85]. FP is a safe and effective treatment for refractory melasma, with long-term remission especially in fairskinned patients.…”

Section: Other Botanicals As Potential Bleaching Agentsmentioning

confidence: 99%

“…FP is a safe and effective treatment for refractory melasma, with long-term remission especially in fairskinned patients. Treatment of patients with skin types III+ should be with extreme caution, since darker skin types are more prone to develop PIH [80,81]. Given the high rate of PIH, FP should not be used at higher fluencies (15 mJ/micro beam) in the treatment of melasma [82].…”

Section: Other Botanicals As Potential Bleaching Agentsmentioning

confidence: 99%

Melasma, Novel Treatment Modalities

Abdallah¹

2014

Pigmentary Disorders

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Treatment of melasma remains challenging due to frequent relapses and the occurrence of post-inflammatory hyperpigmentation (PIH) following many interventions. Treatment goals are inhibition of melanin synthesis and transfer by sunscreens, sun avoidance and the use of bleaching agents on one hand and removal of already present pigment by peeling, lasers and light on the other hand. Triple combination creams (TCC) (also known as Kligman's formula utilizing hydroquinone and modifications of Kligman's formula) remain the mainstay of treatment. Newer bleaching agents derived from plants and synthetic compounds have been introduced and many of them are promising safe substitutes for hydroquinone.Peeling agents especially superficial and medium depth peels are effective treatment modalities for melasma. Newer peeling agents are less irritating and may thus lead to fewer side effects. Q-switched lasers, which target melanin, have led to PIH until the innovation of "laser toning" and fractional Qswitched ruby, which have better outcomes. Fractional non-ablative and ablative lasers are useful at lower fluencies. Pulsed dye laser, which targets the vascular component in melasma, is promising with less melasma rebound.Combinations of the above-mentioned modalities usually have a better treatment outcome than either alone. This review will focus on the more recently introduced therapies.

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Treatment of Melasma Using Fractional Photothermolysis: A Report of Eight Cases with Long-Term Follow-Up

Abstract: FP is a safe and effective treatment for refractory melasma, with long-term remission.

Cited by 48 publications

References 42 publications

Efficacy of Lasers on Pigmentary Lesions

Efficacy of Lasers on Pigmentary Lesions

Fractional Laser Photothermolysis in the Treatment of Skin Defects: Possibilities and Effectiveness (Review)

Melasma, Novel Treatment Modalities

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