Treatment of mandibular ameloblastoma with surgical resection in combination with radiation therapy in a 15‐year‐old Hanoverian gelding

Will, Johanna; Muñoz, Encarnación; Maleh, Souel; Gruber, Achim D.; Coco, Lisa; Fischer, Holger

doi:10.1111/eve.13753

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…Only a few reports describe the use of radiation therapy in horses as an adjuvant treatment for non-cutaneous tumours (Mosunic et al, 2004;Pfeifle et al, 2021;Will et al, 2023), and only one report mentions SBRT in the successful treatment of sinonasal osteosarcoma (Gillen et al, 2020). This is thus the first case report describing radiation therapy as a successful treatment for appendicular osteosarcoma in horses.…”

Section: Discussionmentioning

confidence: 99%

Successful remission of a recurrent osteosarcoma in the second and third metacarpal bones of a warmblood gelding after radiation therapy.

Laekeman,

Haspeslagh,

Oosterlinck

et al. 2024

Preprint

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A fifteen-year-old warmblood gelding was presented with recurrence of a histologically confirmed osteosarcoma of the left second and third metacarpal bones three years after initial diagnosis and treatment. Initially, surgical excision was performed, followed by local injection of carboplatin 11 weeks later. The horse was sound after surgery and was used for low level dressage and jumping. Three years later, the horse developed acute onset of lameness in the left forelimb and a painful soft tissue swelling at the proximomedial metacarpal region. Radiographs showed a spiculated periosteal reaction on the medial aspect of the third metacarpal bone, indicating re-activation of the lesion. Stereotactic radiation therapy was performed with a protocol consisting of three fractions under general anaesthesia (Mo-We-Fr schedule), and a total dose of 30 Gy. The technique used was volumetric modulated arc therapy guided by cone beam computed tomography for daily positioning. Following the radiation therapy, the horse became sound at walk and one month later, it became sound at trot. Follow-up by veterinary examination eighteen months after final treatment revealed no lameness at walk and trot, and a stable radiographic appearance.

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Section: Discussionmentioning

confidence: 99%

Successful remission of a recurrent osteosarcoma in the second and third metacarpal bones of a warmblood gelding after radiation therapy.

Laekeman,

Haspeslagh,

Oosterlinck

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

Successful remission of a recurrent metacarpal osteosarcoma of a Warmblood gelding after radiation therapy

Laekeman,

Haspeslagh,

Oosterlinck

et al. 2024

Equine Veterinary Education

View full text Add to dashboard Cite

SummaryA 15‐year‐old Warmblood gelding was presented with recurrence of a histologically confirmed osteosarcoma of the left second and third metacarpal bones 3 years after initial diagnosis and treatment. Initially, surgical excision was performed, followed by local injection of carboplatin 11 weeks later. The horse was sound after surgery and was used for low‐level dressage and jumping. Three years later, the horse developed an acute onset of lameness in the left forelimb and a painful soft tissue swelling at the proximomedial metacarpal region. Radiographs showed a spiculated periosteal reaction on the medial aspect of the third metacarpal bone, indicating re‐activation of the lesion. Stereotactic radiation therapy was performed with a protocol consisting of three fractions under general anaesthesia (Mo‐We‐Fr schedule), and a total dose of 30 Gy. The technique used was volumetric‐modulated arc therapy guided by cone beam computed tomography for daily positioning. Following the radiation therapy, the horse became sound at walk, and 1 month later, it became sound at trot. Follow‐up by veterinary examination 18 months after final treatment revealed no lameness at walk and trot, and a stable radiographic appearance.

show abstract

Treatment of mandibular ameloblastoma with surgical resection in combination with radiation therapy in a 15‐year‐old Hanoverian gelding

Cited by 2 publications

References 15 publications

Successful remission of a recurrent osteosarcoma in the second and third metacarpal bones of a warmblood gelding after radiation therapy.

Successful remission of a recurrent osteosarcoma in the second and third metacarpal bones of a warmblood gelding after radiation therapy.

Successful remission of a recurrent metacarpal osteosarcoma of a Warmblood gelding after radiation therapy

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