Treatment of malarial acute renal failure by hemodialysis.

Wilairatana, Polrat; Westerlund, Eli; Aursudkij, B; Vannaphan, Suparp; Krudsood, Srivicha; Viriyavejakul, Parnpen; Chokejindachai, Watcharee; Treeprasertsuk, Sombat; Srisuriya, Pranee; Gordeuk, Victor R.; Brittenham, Gary M.; Neild, Guy H.; Looareesuwan, Sornchai

doi:10.4269/ajtmh.1999.60.233

Cited by 38 publications

(26 citation statements)

References 17 publications

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“…The association between renal failure and jaundice is a recurrent finding in studies on severe malaria. [14][15][16][17] Acute renal failure can be found both in patients with and without cerebral malaria. 15 In the case of isolated acute renal failure, considering cytoadherence as the major mechanism would imply that it must be organ selective, because cerebral function is highly sensitive to vascular disturbances.…”

Section: Discussionmentioning

confidence: 99%

“…[14][15][16][17] Acute renal failure can be found both in patients with and without cerebral malaria. 15 In the case of isolated acute renal failure, considering cytoadherence as the major mechanism would imply that it must be organ selective, because cerebral function is highly sensitive to vascular disturbances. However, in our logistic regression models, schizont counts and their relative proportion to ring forms, which reflect the proportion of sequestrated parasites, 9 were not risk factors when compared with moderately severe con-trols.…”

Section: Discussionmentioning

confidence: 99%

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Association of hepatomegaly and jaundice with acute renal failure but not with cerebral malaria in severe falciparum malaria in Thailand.

Treeprasertsuk¹,

Singhasivanon²,

Silachamroon³

et al. 2001

The American Journal of Tropical Medicine and Hygiene

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Abstract. We conducted a case record study comparing liver tests abnormalities in 20 malaria-related acute renal failure cases without cerebral malaria, 52 cerebral malaria cases without other organ impairment, 189 cases of nonsevere malaria associated with a high parasite burden, and 131 cases of mild Plasmodium falciparum malaria. Jaundice and hepatomegaly were significantly associated with renal failure (adjusted odds ratio [AOR], 3.3, 95% confidence interval [CI], 1.3-8.6, P ϭ 0.01; and AOR, 1.7 95% CI, 1.13-2.4, P ϭ 0.01) but not with cerebral malaria (AOR, 1, 95% CI, 0.5-2, P ϭ 0.8; and AOR, 1.08, 95% CI, 0.8-1.8, P ϭ 0.5). Patients with acute renal failure were significantly older and had increased liver abnormalities compared with other groups. Although an increase in the proportion of mature schizonts over ring forms was significantly associated with cerebral malaria, it did not seem to have affected acute renal failure. These results suggested that cytoadherence was not the main determinant for renal failure and that jaundice itself may have potentiated the effects of hypovolemia.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Association of hepatomegaly and jaundice with acute renal failure but not with cerebral malaria in severe falciparum malaria in Thailand.

Treeprasertsuk¹,

Singhasivanon²,

Silachamroon³

et al. 2001

The American Journal of Tropical Medicine and Hygiene

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“…Similar observations were reported in a study from Thailand, where 58.3% patients died during the first 24 h after admission. 28 Concomitant presence of cerebral malaria was noted in 22 patients, out of which 6 patients died. Thus, the presence of cerebral malaria significantly predicted adverse outcome (p ¼ 0.002).…”

Section: Discussionmentioning

confidence: 99%

Outcome of malaria-associated acute kidney injury: a prospective study from a single center

et al. 2013

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“…Fluid overload in the presence of renal failure and severe anemia can precipitate cardiogenic pulmonary edema, and early institution of renal replacement therapy may limit pulmonary complications. 56 Loop diuretics help reduce the risk of volume overload in the setting of renal failure and should be available in the operating room. Renal failure can affect the handling of many anesthetic drugs.…”

Section: Perioperative Considerations Of Malaria 313mentioning

confidence: 99%

Perioperative considerations of the patient with malaria

Soltanifar

Carvalho

Sultan

2014

Can J Anesth/J Can Anesth

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Purpose Malaria is a life-threatening infectious disease caused by the Plasmodium parasite. Increased global travel has resulted in an escalation in the number of imported cases seen in developed countries. Patients with malaria may present for surgery in both endemic and nonendemic countries. This article reviews the perioperative considerations when managing patients with malaria. Source A literature review of anesthesia, perioperative care, and malaria-related articles was performed using the MEDLINE Ò , EMBASE TM , and Web of Science databases to identify relevant articles published in English during . Of the 303 articles matching the search criteria, 265 were excluded based on title and abstract. Eleven of the remaining 38 articles were relevant to anesthesia/perioperative care, and 27 articles were identified as having direct relevance to critical care medicine. Principal findings The majority of imported malaria cases are caused by the falciparum species, which is associated with the greatest degree of morbidity and mortality. Various organ systems may be impacted as a consequence of changes in the structure and function of parasitized erythrocytes. Preoperative assessment should focus on establishing the species of malaria, the severity of disease, assessing the degree of end-organ impairment, and initiating treatment of malaria prior to surgery. Intravenous artesunate is the treatment of choice for severe falciparum malaria. Quinine is a second-line agent but has a narrow therapeutic index and particularly hazardous side effects. Intraoperatively, attention should focus on fluid management, dynamics of cerebral blood flow, and avoidance of hypoglycemia. Postoperative care of severe cases should ideally take place in a critical care unit as there may be ongoing requirements for multi-organ support, including renal replacement therapy, ventilation, and/or inotropic support. The safety of neuraxial anesthesia has not been well studied in the setting of malaria. Conclusions Malaria remains one of the most devastating infectious diseases worldwide. Multiple organ systems can be impacted as a consequence of changes in structure and function of parasitized erythrocytes. Safe perioperative management requires a sound knowledge of all these potential system effects. RésuméObjectif Le paludisme est une maladie infectieuse possiblement fatale due au parasite Plasmodium. La multiplication des voyages à travers le monde a entraîné un accroissement du nombre de cas importés observés dans les pays développés. Les patients atteints de paludisme peuvent nécessiter une chirurgie, aussi bien dans les pays où la maladie est endémique que dans les autres. Cet article passe en revue les considérations périopératoires lors de la prise en charge de patients atteints de paludisme. Source Une revue de la littérature à la recherche d'articles d'anesthésie, de soins périopératoires et en Author contributions Daniel Soltanifar, Brendan Carvalho, and Pervez Sultan all made substantial contributions to the literature review, ...

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Treatment of malarial acute renal failure by hemodialysis.

Cited by 38 publications

References 17 publications

Association of hepatomegaly and jaundice with acute renal failure but not with cerebral malaria in severe falciparum malaria in Thailand.

Association of hepatomegaly and jaundice with acute renal failure but not with cerebral malaria in severe falciparum malaria in Thailand.

Outcome of malaria-associated acute kidney injury: a prospective study from a single center

Perioperative considerations of the patient with malaria

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