“…In recent years, some reports on the treatment of granulomatous diseases have suggested the efficacy of tetracyclines in the treatment of sarcoidosis, 2 efficacy of minocycline in the treatment of Melkersson-Rosenthal syndrome, 3 and the efficacy of roxithromycin in the treatment of lupus miliaris disseminatus fasciei. 4 Roxithromycin as well as minomycin have been reported to be effective in the treatment of confluent and reticulated papillomatosis, which is mainly characterized by epidermal papillomatosis, hyperkeratosis and hyperpigmentation of the basal layer. 5 As shown in the present study, roxithromycin was efficient in a patient with granulomatous cheilitis.…”