Treatment of lower urinary tract infection in pregnancy

Krčmery, S.; Hromec, J; Demesova, D.

doi:10.1016/s0924-8579(00)00351-4

Cited by 90 publications

(59 citation statements)

References 11 publications

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“…[399][400][401][402][403][404][405][406] Further details of the review can be found in Appendix 6, Table 118. The quality of the included studies was variable and poor in terms of blinding and allocation concealment ( Figure 112).…”

Section: Antibiotics For Symptomatic Urinary Tract Infectionsmentioning

confidence: 99%

Screening to prevent spontaneous preterm birth: systematic reviews of accuracy and effectiveness literature with economic modelling

Honest

Ca²,

Durée³

et al. 2009

Health Technol Assess

182

146

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For primary prevention, an effective, affordable and safe intervention applied to all mothers without preceding testing is likely to be the most cost-effective approach in asymptomatic women in early pregnancy. For secondary prevention among women at risk of preterm labour in later pregnancy, a management strategy based on the results of testing is likely to be more cost-effective. Implementation of a treat-all strategy with simple interventions, such as fish oils, would be premature for asymptomatic women. Universal provision of high-quality ultrasound machines in labour wards is more strongly indicated for predicting spontaneous preterm birth among symptomatic women than direct management, although staffing issues and the feasibility and acceptability to mothers and health providers of such strategies need to be explored. Further research should include investigations of low-cost and effective tests and treatments to reduce and delay spontaneous preterm birth and reduce the risk of perinatal mortality arising from preterm birth.

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Section: Antibiotics For Symptomatic Urinary Tract Infectionsmentioning

confidence: 99%

Screening to prevent spontaneous preterm birth: systematic reviews of accuracy and effectiveness literature with economic modelling

Honest

Ca²,

Durée³

et al. 2009

Health Technol Assess

182

146

View full text Add to dashboard Cite

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“…4 It can cause maternal anemia, acute pyelonephritis, recurrent infection, preterm labour, 5 septicemia and even death of the mother. 6 It can cause intra uterine growth restriction 7 prematurity and low birth weight of the fetus 8 and fetal mortality 9 .There is an increased chance of urinary tract infection in females as compared to males due to short urethra (4cm), proximity to the anus contaminated heavily with microorganisms. 10 Urinary tract infections are more common in pregnants than non-pregnants because urinary tract undergoes profound physiologic and anatomic changes during pregnancy that facilitates the development of symptomatic urinary tract infections in the women with bacteriuria.…”

mentioning

confidence: 99%

Prevalence of Asymptomatic Bacteriuria in Antenatal Women Coming to NRIMC&GH

Ramalingam

Surasani

Bollu

2016

Bangladesh J Obstet Gynaecol

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Objective(s):The aim of the study was to determine the prevalence of asymptomatic bacteriuria in pregnant women attending the antenatal OPD and to treat them. Also to identify the organisms causing asymptomatic bacteriuria and the risk factors in pregnant women.Materials and Methods: The present observational study was conducted in the Department of Obstetrics, NRI Medical College, Chinakakani, Mangalagiri from Aug-2012 to Aug-2014. Material for the study consisted of 100 urine samples obtained from asymptomatic 100 pregnant women in their first antenatal visit. The study group consisted of cases from in and around Mangalagiri, attending antenatal OPD, NRI Medical College, Chinakakani. Each patient was first asked whether she had any symptom of urinary tract infection such as dysuria, urgency, haematuria, loin pain and fever. After ascertaining that she was asymptomatic, preliminary data on maternal age, gravidity, parity and period of gestation were collected on a predesigned proforma. Detailed history about previous antenatal check-up, hypertension were also taken. A clean-catch midstream urine sample was collected and MacConkey agar, Blood agar plates were used for culture .Bacterial counts were done to determine the number of microorganisms per millilitre.Antimicrobial susceptibility testing was done for the isolates by the Kirby-Bauer method (disc diffusion).Results: The prevalence of asymptomatic bacteriuria in the study group was 15%.Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus saprophyticus, Staphylococcus aureus were the isolates in the study group. Isolates showed maximum susceptibility to gentamycin followed by cefotaxime, nitrofurantoin and cotrimoxazole. They showed high degree of resistance to cephalexin and ceftriaxone. All the asymptomatic pregnant women with significant bacteriuria were treated and asked to come back after 7-10 days for repeat culture and susceptibility testing, which was done as a part of follow-up.Conclusion: Increasing gestational period showed increase in the incidence of asymptomatic bacteriuria and also increased incidence was seen in the pregnants with anaemia. Routine antenatal screening for asymptomatic bacteriuria should be implemented and treatment of those showing bacteriuria must be practiced to prevent adverse perinatal outcome. Untreated asymptomatic bacteriuria progresses to pyelonephritis (13-27%). Therefore, routine screening for bacteriuria is recommended during pregnancy.Bangladesh J Obstet Gynaecol, 2015; Vol. 30(1) : 30-36

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“…55,199 More recently, it has been compared with ceftibuten 400 mg once daily for three days, with a 95% therapeutic success rate (clinical cure and bacteriological eradication). 206 In the treatment of asymptomatic bacteriuria, a single dose of fosfomycin trometamine showed the same level of therapeutic success as cefuroxime axetyl for five days (93.2% versus 95%), 207 and as amoxicillin + clavulanic acid for seven days (eradication rate over 80% in both groups). 208 A single 2 g dose of fosfomycin trometamine was also compared with pipemidic acid 200 mg twice daily for seven days in children weighing more than 25 kg.…”

Section: Clinical Studiesmentioning

confidence: 93%

Fosfomycin and Its Application in the Treatment of Multidrug-Resistant Enterobacteriaceae Infections

2011

Clinical Medicine Reviews in Therapeutics

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Abstract:The use of fosfomycin has been limited in therapeutics in recent years. Because it has shown good antibacterial activity in vitro and clinical efficacy in some domains, it has been proposed as an alternative to current antimicrobial agents, which are subject to increasing resistance. This paper reviews the main properties of fosfomycin and the latest publications concerning multidrugresistant Enterobacteriaceae infections. In uncomplicated urinary tract infections, a single oral dose was found to be safe and effective. In complicated urinary tract infections, the same results were observed with several doses. In both cases, by using fosfomycin to treat infections, the use of carbapenems could be reduced, leading to lower costs and better microbial ecology. In severe infections, combinations with intravenous fosfomycin need to be explored further because its future activity may depend on choosing a good partner drug. Because of the fast evolution of microbial resistance, more studies are urgently needed.

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Treatment of lower urinary tract infection in pregnancy

Cited by 90 publications

References 11 publications

Screening to prevent spontaneous preterm birth: systematic reviews of accuracy and effectiveness literature with economic modelling

Screening to prevent spontaneous preterm birth: systematic reviews of accuracy and effectiveness literature with economic modelling

Prevalence of Asymptomatic Bacteriuria in Antenatal Women Coming to NRIMC&GH

Fosfomycin and Its Application in the Treatment of Multidrug-Resistant Enterobacteriaceae Infections

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