Treatment of localized mycosis fungoides with digital <scp>UV</scp> photochemotherapy

Reidel, Ulrich; Bechstein, Sarah; Lange‐Asschenfeldt, Bernhard; Beyer, Marc; Vandersee, Staffan

doi:10.1111/phpp.12196

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Cited by 3 publications

(1 citation statement)

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“…, lower panel) using the digitized pixel rays (by 13·68 × 13·68 μm) of the skintrek technology. Targeted digital phototherapy with skintrek PT3 has recently been successfully administered to patients with psoriasis and mycosis fungoides …”

mentioning

confidence: 99%

Digital ultraviolet B phototherapy in vitiligo: proof of concept

2019

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mentioning

confidence: 99%

Digital ultraviolet B phototherapy in vitiligo: proof of concept

2019

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Recent Advances in Pathogenesis and Medical Management of Vitiligo

T¹,

Parsad²

2018

Pigmentary Skin Disorders

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Machine learning for automated, targeted, phototherapy

Praeger,

Scott,

Grant-Jacob

et al. 2024

Opt. Continuum

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This work combines two existing technologies to demonstrate the possibility for automated, targeted, phototherapy of psoriasis and other skin conditions: 1) Image-to-image translation via a neural network (NN) as a method of image segmentation. 2) Light control using a digital micromirror device (DMD). With a small dataset of just 104 patient photographs (labeled by expert dermatologists) our NN model was trained to identify regions of psoriasis that required treatment, achieving an average accuracy of 96.6%. The image output of the NN model was applied to a DMD and precise control over the shape of the illuminated region was demonstrated. In the proposed automated phototherapy device this would target treatment to the affected regions, minimizing exposure of healthy skin and the associated risks of patient harm.

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Treatment of localized mycosis fungoides with digital UV photochemotherapy

Abstract: This study is the first prospective trial demonstrating efficacy and safety of cream PUVA in MF patients. As healthy adjacent skin remains unaffected, the potential to reduce the carcinogenic risk of PUVA treatment makes this new method a promising therapeutic option for localized MF.

Cited by 3 publications

References 28 publications

Digital ultraviolet B phototherapy in vitiligo: proof of concept

Digital ultraviolet B phototherapy in vitiligo: proof of concept

Recent Advances in Pathogenesis and Medical Management of Vitiligo

Machine learning for automated, targeted, phototherapy

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