Treatment of Late Recurrent Vaginal Malignancy after Initial Radiotherapy for Carcinoma of the Cervix: An Analysis of 73 Cases

Xiange, Wang; Cai, San Jun; Ding, Yaqin; Wei, Ke

doi:10.1006/gyno.1998.4975

Cited by 21 publications

(10 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is difficult but also necessary to determine when we should cease follow up, because of the limited capacity of facilities and the issue of cost‐effectiveness. However, especially younger patients who received radiotherapy for initial treatment might benefit by continued follow‐up over many years, because they could undertake aggressive treatment if early diagnosis was possible in the case of recurrence of smaller‐sized cancer 8–11 . The present study indicated that it would be useful to select the patients who should be followed up for a long period by considering their risk factors for recurrence, that is, prior radiotherapy treatment or advanced primary disease necessitating adjuvant or primary radiotherapy, including lymph node metastasis.…”

Section: Discussionmentioning

confidence: 89%

Late recurrence of invasive cervical cancer: Twenty years’ experience in a single cancer institute

Gotō

Kino

Shirai

et al. 2005

J of Obstet and Gynaecol

View full text Add to dashboard Cite

Late recurrence of cervical cancer was frequently observed in patients with initial treatment, including radiotherapy. Some had very long disease-free intervals, but many were diagnosed by ordinary internal or external examination or chest X-ray. Patients with primary surgery experienced recurrence less frequently in the case of lymph node metastasis than was the case for hematogenous metastasis. Radiotherapy was effective and improved prognosis, especially for recurrence of cancer outside the irradiated field.

show abstract

Section: Discussionmentioning

confidence: 89%

Late recurrence of invasive cervical cancer: Twenty years’ experience in a single cancer institute

Gotō

Kino

Shirai

et al. 2005

J of Obstet and Gynaecol

View full text Add to dashboard Cite

show abstract

“…Other treatments include reirradiation or interstitial irradiation offering local control rates of 64 -92% along with a 5-year survival rate of 4 -44% for recurrent cervical cancer. However, a high rate of severe complications has been reported in both the urinary and lower gastrointestinal tracts (Russell et al, 1987;Sommers et al, 1989;Xiang-E et al, 1998). With respect to surgical treatment for residual disease after radiation therapy, the most effective method is probably pelvic exenteration (Stanhope et al, 1990).…”

Section: Discussionmentioning

confidence: 99%

Adjuvant hysterectomy for treatment of residual disease in patients with cervical cancer treated with radiation therapy

et al. 2008

View full text Add to dashboard Cite

The objective of this retrospective study was to determine the efficacy of adjuvant hysterectomy for treatment of residual disease in cervical carcinoma treated with radiation therapy. Between 1971 and 1996, 1590 patients with carcinoma of the uterine cervix (stages I -IIIb) were treated with radiation therapy. Three months after completion of radiation therapy, the status of local control was investigated, and total abdominal hysterectomy was performed in cases in which central residual disease existed in the cervix. Of the 1590 patients, residual disease was identified in 162 patients. Among these patients, 35 showed an absence of distant metastasis or lateral parametrial invasion and underwent hysterectomy. The overall 5-and 10-year survival rates for these patients were 68.6 and 65.7%, respectively. There was no significant difference in survival between patients with squamous cell carcinoma and those with non-squamous cell carcinoma or between patients with stage I/II carcinoma and those with stage III carcinoma. With respect to treatment-related morbidity, five (14.3%) patients suffered grade III or IV complications after hysterectomy. Adjuvant hysterectomy is an effective addition to radiation therapy in the treatment of cervical cancer, even in patients with stage III disease and in those with non-squamous cell carcinoma.

show abstract

“…Reirradiation has also been used successfully in the management of recurrent gynecologic malignancies, although interstitial implantation of iridium-192 or 125 I was used. [37][38][39] Hyperfractionated radiation has also led to safe radiation dose escalation while avoiding critical late injuries by limiting the toxicity to slowly proliferating normal tissues. 40 The addition of chemotherapy as a radiation sensitizer has improved the efficacy of radiation treatments, 41 allowing better local tumor control without increasing dose-limiting late effects.…”

Section: Discussionmentioning

confidence: 99%

Long‐term results of reirradiation for patients with recurrent rectal carcinoma

Mohiuddin

Marks

2002

Cancer

189

136

View full text Add to dashboard Cite

An adaptive extremum seeking control scheme for a class of nonlinear distributed parameter systems is presented. It addresses the real‐time optimization of a parallel chemical reaction system in an isothermal tubular reactor with uniform distributed feed described by a set of hyperbolic partial differential equations. Only limited knowledge of the kinetics is assumed. An adaptive learning technique is introduced to design an extremum seeking algorithm that drives the system states to a set point that maximizes the value of an objective function. Lyapunov's stability theorem is used in the design of the extremum seeking controller structure and the development of the parameter learning laws. © 2006 American Institute of Chemical Engineers AIChE J, 2006

show abstract

Treatment of Late Recurrent Vaginal Malignancy after Initial Radiotherapy for Carcinoma of the Cervix: An Analysis of 73 Cases

Cited by 21 publications

References 8 publications

Late recurrence of invasive cervical cancer: Twenty years’ experience in a single cancer institute

Late recurrence of invasive cervical cancer: Twenty years’ experience in a single cancer institute

Adjuvant hysterectomy for treatment of residual disease in patients with cervical cancer treated with radiation therapy

Long‐term results of reirradiation for patients with recurrent rectal carcinoma

Contact Info

Product

Resources

About