Treatment of large odontogenic keratocysts by decompression and later cystectomy

Conservative management of keratocystic odontogenic tumour in a young child with decompression and an intraoral appliance: 5-year follow-up

“…August et al 17 in their study have demonstrated epithelial dedifferentiation and loss of keratinisation with decompression and irrigation. However, there are few limitations of decompression as it requires patient compliance, may fail to completely eradicate lesion or there may be some malignant changes in the cavity which may go undiagnosed, and this technique may require secondary enucleation 18. The resolution of KCOTs after marsupialisation is also considered by some to be non-compatible with a neoplastic process and one of the reasons of reclassifying the lesion to the cystic category in 2017 14…”

Two-stage treatment protocol of keratocystic odontogenic tumour in young patients with Gorlin–Goltz syndrome: Marsupialization and later enucleation with peripheral ostectomy. A 5-year-follow-up experience

“…Marker et al [39] evaluated the changes in the epithelium of 23 keratocysts, 18 of which classified as KCOT involving specially the angle/ramus region, after a 1-year average decompression treatment. Histologic examination performed on the tissue removed at cystectomy showed that in 19 cases decompression resulted in the cyst epithelium changing type.…”

Conventional Endodontic Therapy of Upper Central Incisor Combined with Cyst Decompression: A Case Report

“…Others report a secondary surgery for enucleation of the residual (albeit much smaller) cyst. These latter case reports involved extensive lesions in the mandible (20,21).…”