Treatment of Labial Herpes

Gr, Nugent; Sm, Chou

doi:10.1001/jama.1973.03220140100030

Cited by 14 publications

(3 citation statements)

References 1 publication

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“…Positive Studies. Nugent and Chou (1973) first described their experiences treating themselves and a few colleagues in an anecdotal letter to the editor. They reported 100% success (N = 6) in preventing lesions from progressing beyond early stages and in decreasing the number of recurrences.…”

Section: Organic Solvents (Ethyl Ether and Chloroform) For Treating Hsvmentioning

confidence: 99%

The power of nonspecific effects in healing: Implications for psychosocial and biological treatments

Roberts

Kewman

Mercier

et al. 1993

Clinical Psychology Review

155

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We evaluate the hypothesis that the power of nonspecific ejects may account for as much as two thirds of successful treatment outcomes when both the healer and the patient believe in the efficacy of a treatment. Five medical and surgical treatments, once considered to be eJiicacious by their proponents but no longer considered effective based upon later controlled trials, were selected according to strict inclusion criteria. A search of the English literature was condtutedfor all studies published for each treatment area. The results of these studies were categorized, where possible, into excellent, good, and poor outcomes. For these five treatments combined, 40% excellent, 30% good, and 30% poor results were reported by proponents. We conclude that, under conditions of heightened expectations, the power of nonspeczfic eflects far exceeds that commonly reported in the literature. The implications of these results in evaluating the relative eflicacy of biological and psychosocial treatments is discussed. The issue of specific and nonspecific effects in psychiatric and psychological interventions continues to be a matter of intense interest and debate. Controversies involve both biological (Fisher & Greenberg, 1989a; Margraf et al., 1991) and psychosocial (Beutler,

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Section: Organic Solvents (Ethyl Ether and Chloroform) For Treating Hsvmentioning

confidence: 99%

The power of nonspecific effects in healing: Implications for psychosocial and biological treatments

Roberts

Kewman

Mercier

et al. 1993

Clinical Psychology Review

155

View full text Add to dashboard Cite

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“…A wide range of agents and procedures which are able to inhibit or suppress HSV replication in vivo or in vitro with varying degrees of success have emerged (with others being added to the list continually). Noteworthy among these are: several antimitotic chemicals (253), cancer cell extracts (2), human gamma globulin (1), trifluorothymidine (261), trifluorodeoxyuridine (124), lysine (123), iododeoxycytidine (144), iododeoxyuridine (IudR or IDU; 56, 138, 261), polyinosinic-cytidylic acid (179,231,260), interferon (126), ara-c (109), ara-c with L-asparaginase (34), arabinofuranosyladenine (138,200), phosphonoacetic acid (238), adenine arabinoside (45,199), rifamycin (181), ethyl ether (186), various photodynamic dyes (1C4), X irradiation (7,139), a vaccinia virus vaccine (72), a herpesvirus vaccine (127, 251), cryotherapy (19,83,104), and psychotherapy (25). However, HSV has proven to be resistant to glutathione (124), fl-methazone (124), pyran copolymers (231), lysozyme (124), 6-azauridine (138), and kethoxal (256).…”

Section: Treatment Of Recurrent Hsvmentioning

confidence: 99%

The latent herpes simplex virus.

Docherty¹,

Chopan²

1974

Bacteriological Reviews

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“…It has been shown through tissue culture that the infectivity of the virus is removed by dissolving the lipid coat in various solvents. Ether applied topically has been used in the treatment of labial herpes [20].…”

Section: Introductionmentioning

confidence: 99%

A Multicentered Study of Lysine Therapy in Herpes simplex Infection

Griffith

Norins

Kagan³

1978

Dermatology

100

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Lysine appears to suppress the clinical manifestations of herpesvirus infection. 45 patients with frequently recurring herpes infection were given 312–1,200 mg of lysine daily in single or multiple doses. The clinical results demonstrated a beneficial effect from supplementary lysine in accelerating recovery from herpes simplex infection and suppressing recurrence. Tissue culture studies have demonstrated an enhancing effect on viral replication when the amino acid ratio of arginine to lysine favors arginine. The opposite, preponderance of lysine to arginine, suppresses viral replication and inhibits cyto-pathogenicity of herpes simplex virus. The codons characterizing herpes simplex DNA apparently specify production of viral capsids at the expense of host cell histones.

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Treatment of Labial Herpes

Cited by 14 publications

References 1 publication

The power of nonspecific effects in healing: Implications for psychosocial and biological treatments

The power of nonspecific effects in healing: Implications for psychosocial and biological treatments

The latent herpes simplex virus.

A Multicentered Study of Lysine Therapy in Herpes simplex Infection

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