Treatment of injection‐induced ecchymoses with light/laser‐assisted technology

Verner, Ines; Naveh, Hadas Prag; Bertossi, Dario

doi:10.1111/dth.12861

Cited by 15 publications

(17 citation statements)

References 9 publications

(18 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, all of these have very limited results, if any, and there have been no large‐scale studies proving their long‐term efficacy for this condition. Considering IPL is used to decrease postprocedural purpura [28,32], is associated with a significantly altered expression of RNAs similar to that in youthful skin [37], decreases superficial telangiectasia [27], and increases collagen production and epidermal thickening [20], it appears to be an ideal option for the treatment and prevention of senile purpura.…”

Section: Discussionmentioning

confidence: 99%

“…In 2018, Narurkar [28] reported that after utilizing an IPL device in 15 subjects, there was a reduction of postfiller bruising ranging from 70% to 100% in all subjects with a mean reduction of 85%; however, there was no control group in this study. Most recently in 2019, Verner et al [32] documented complete resolution of postinjection bruising within 48 hours on all 11 subjects using a narrow‐band IPL, emitting light mainly between 500 and 600 nm.…”

Section: Introductionmentioning

confidence: 99%

“…While multiple lasers and light sources target hemoglobin, such as the 585 or 595 nm PDL, the 532 or 1064 nm neodymium‐doped yttrium aluminum garnet (Nd:YAG) lasers, and IPL [32,33], only IPL produces a broad spectrum of wavelengths that targets not only oxyhemoglobin but also its breakdown products, such as biliverdin, bilirubin, and hemosiderin, each with their own absorption peaks. Absorption peaks for oxyhemoglobin include 418, 542, and 577 nm [34], while bilirubin's peak absorption spectrum is 464 nm [35], and hemosiderin ranges from 660 to 680 nm [36].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Intense Pulsed Light as a Treatment for Senile Purpura: A Pilot Study

Siperstein

Wikramanayake

2020

Lasers Surg Med

View full text Add to dashboard Cite

Background and Objectives Senile purpura is a common condition characterized by recurrent ecchymoses in the elderly on the extensor surfaces of the forearms, hands, and legs. Our objective is to assess the efficacy and safety of a protocol using intense pulsed light (BBL; Sciton Inc., Palo Alto, CA) to improve the appearance of senile purpura on subjects' extensor forearms. Study Design/Materials and Methods Five subjects over 65 years of age, with ecchymotic lesions measuring over 1 cm on each forearm and five younger subjects under 35 years of age, without any ecchymotic lesions, were included in the study. The subjects were treated on one randomized forearm with a new intense pulsed light protocol for four weekly sessions. Photographs and subject questionnaires were taken weekly before each treatment as well as 1 month after all treatments. Skin biopsies were taken 1 day after the last of four weekly treatments. Histological analysis, including hematoxylin and eosin, elastic van Gieson, and Masson's Trichrome staining, were carried out to assess both the epidermal thickness and dermal connective tissue structure. The protocol consists of multiple passes using an intense pulsed light (BBL; Sciton Inc.) device in which the wavelength, filter, and fluence are adjusted for each step. Step 1 uses infrared light (800–1,400 nm), high intensity, a smooth adapter, and a constant motion technique. Step 2 employs a 590‐nm filter with two different fluences and step 3 utilizes a 560‐nm filter. The fluence of steps 2–3 is increased by 1 J each treatment if no side effects are noted. Results Using a new intense pulsed light protocol in subjects with senile purpura, both the number and square area of ecchymoses on the treated arm were significantly reduced (P = 0.02 and P = 0.04, respectively, paired t test) as compared with the untreated arm at 1 month after four weekly treatments. Despite this pilot study including challenging cases of subjects on both inhaled and injected corticosteroids and blood thinners, all subjects with senile purpura had at least a 50% reduction in the total square area of their ecchymoses on their treated arm. There were no significant or long‐lasting side effects, and all subjects reported satisfaction with the treatment with a desire to continue treatments on their control arm. Blinded evaluators were able to select 100% of the time in the subjects with senile purpura, which was the treated arm as compared with the control arm when reviewing photographs from 1 month after the last treatment. In addition, several subjects were noted to have a significant improvement in the appearance of hemosiderin deposition and photodamage. Histologically, intense pulsed light treatments significantly increased epidermal thickness in elderly subjects by 21.14% (P = 0.0153, two‐tailed, paired t test), to levels comparable with young subjects. Such restoration is consistent with the other histological observations by blinded evaluators of more abundant and organized collagen fibers in the dermis and reduced aggreg...

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Intense Pulsed Light as a Treatment for Senile Purpura: A Pilot Study

Siperstein

Wikramanayake

2020

Lasers Surg Med

View full text Add to dashboard Cite

show abstract

“…10,11 As bruising is caused by extravasation of blood and subsequent release of hemoglobin to the interstitial space, selective photothermolysis with light/laser therapy can be used to treat bruises, 12 with hemoglobin serving as the chromophore. 13 There are sufficient number of studies suggesting that pulsed dye laser (PDL) 10,12,14,15 or intense pulsed light (IPL) 5 accelerates bruise resolution. The Nd:YAG wavelength is highly absorbed by the hemoglobin in the tissue.…”

Section: Introductionmentioning

confidence: 99%

Use of Nd:YAG laser in bruise resolution caused by an injectable dermal filler procedure

Dekeyser¹,

Wellens²,

Talaber

2022

Clinical Case Reports

View full text Add to dashboard Cite

Injectable dermal fillers are in high demand. Patients undergoing this treatment are frequently burdened by bruising in the days following the procedure. Bruises associated with dermal fillers usually resolve spontaneously within 10 to 14 days, but patients want shorter downtime. We present a case of a bruise treatment with Nd:YAG laser consisting of three sessions in two day intervals, where the bruise resolved after seven days from the start of laser treatment. To date, the reports on laser therapy for bruise resolution are mostly limited to intense pulsed light and pulsed dye laser, and this case report contributes to the demonstration of Nd:YAG laser efficacy for this indication.

show abstract

“…Atualmente, há na literatura artigos demostrando os benefícios do uso de luzes como Luz Intensa Pulsada e Lasers 4 , e o uso de substâncias com ação antiinflamatória, antiexsudativa, anticoagulante, antitrombótica e fibrinolítica como o Polissulfato de Mucopolissacarídeo e a arnica montana 5 e outras substância, como a Bromelina, por exemplo 6 .…”

Section: Introductionunclassified

Fotobiomodulação associada a antioxidante quelante no tratamento de equimose/hematoma na região periorbicular após injeção de bioestimulador

Bello¹

2020

Aesth Orofacial Sci

View full text Add to dashboard Cite

O presente caso clínico teve como objetivo o tratamento de hematoma e equimose após procedimento estético através da associação da fotobiomodulação e agente antioxidante. A importância do manejo adequado se da pelo fato da presença da afecção ocasionar estresse psicológico, podendo ainda ser o fator desencadeante da hiperpigmentação pós inflamatória periocular. Detalhamento do caso: paciente do sexo feminino, 48 anos, portadora de alterações hepáticas congênitas, apresentou equimoses e hematomas após procedimento injetável com o uso de bioestimuladores. A conduta clínica da mesma foi submetê-la á fotobiomodulação através do uso da luz amarela emitida por diodo LED em 590 nm associada ao laser infravermelho em 808 nm simultaneamente em regime contínuo e pulsado, juntamente com uso de antioxidantes tópico e sistêmico para tratamento da coleção sanguinolenta e clareamento da área acometida. Conclusão: a fotobiomodulação e antioxidantes mostraram-se eficazes na resolução da equimose e hematoma, sem evoluir para hiperpigmentação pós inflamatória periocular.

show abstract

Treatment of injection‐induced ecchymoses with light/laser‐assisted technology

Cited by 15 publications

References 9 publications

Intense Pulsed Light as a Treatment for Senile Purpura: A Pilot Study

Intense Pulsed Light as a Treatment for Senile Purpura: A Pilot Study

Use of Nd:YAG laser in bruise resolution caused by an injectable dermal filler procedure

Fotobiomodulação associada a antioxidante quelante no tratamento de equimose/hematoma na região periorbicular após injeção de bioestimulador

Contact Info

Product

Resources

About