Treatment of infertility in women

Smith, Carriann; Grimm, Maureen; Schwegel, Megan

doi:10.1016/s1042-0991(15)31824-7

Cited by 2 publications

(10 citation statements)

References 34 publications

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“…Data suggest no increase in the rates of spontaneous abortion or congenital anomalies with clomiphene use compared to rates in the general population. 7,37…”

Section: Pharmacologic Managementmentioning

confidence: 99%

“…In studies, clomiphene was associated with a significantly higher incidence of hot flushes; however, letrozole was associated with a significantly higher incidence of fatigue and dizziness. 7,40 -42 Anastrozole and letrozole have been used off-label for male infertility to increase testosterone, decrease estrogen, and inhibit peripheral metabolism of testosterone. 36…”

Section: Pharmacologic Managementmentioning

confidence: 99%

“…Women with PCOS who have not ovulated or conceived with weight loss, clomiphene, or letrozole therapy and hypogonadotropic anovulatory women with hypopituitarism or women with hypothalamic amenorrhea without access to pulsatile GnRH therapy are candidates for gonadotropin therapy. 7…”

Section: Pharmacologic Managementmentioning

confidence: 99%

“…Human hCG and recombinant hCG (r-hCG) are FDA-approved ovulatory triggers given 24 to 36 hours prior to planned insemination. 7 A dose of 250 µg of r-hCG appears to be equivalent to 5000 to 6000 units of hCG. 56 Formulations appear to have similar efficacy in terms of live birth, ongoing pregnancy rates, and rates of OHSS.…”

Section: Pharmacologic Managementmentioning

confidence: 99%

“…Hypothalamic–pituitary dysfunction is described by normal estrogen and FSH concentrations and as a gonadotropin disorder, and over 90% of these patients have polycystic ovary syndrome (PCOS). 6 -8 The main etiologies of male infertility include infection, injury, toxin exposure, variances in anatomy or chromosomes, systemic disease, and sperm-directed antibodies. 4…”

Section: Introductionmentioning

confidence: 99%

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Infertility Management and Pharmacotherapy: What Every Pharmacist Should Know

Cieri‐Hutcherson

Harris

Karaoui

et al. 2020

Journal of Pharmacy Practice

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Infertility is a significant public health concern in the United States. As such, utilization of infertility services, including pharmacotherapeutic treatments, is prevalent, and the role of the pharmacist as part of the health care team is essential. Pharmacists can assist patients by providing education on infertility causes, risk factor mitigation, referrals, nonpharmacologic and pharmacologic management options, navigation of the prescription process, and resource availability for the significant financial burden accompanying infertility treatment. In-depth pharmacotherapeutic information may not be readily available to pharmacists dispensing and counseling on these medications, and infertility management regimens are often varied and complicated requiring more in-depth counseling on use and administration. Given the complexity of infertility management, pharmacists are a valuable patient support and education resource. This article provides an in-depth review of infertility management strategies, both nonpharmacologic and pharmacologic.

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“…Data suggest no increase in the rates of spontaneous abortion or congenital anomalies with clomiphene use compared to rates in the general population. 7,37…”

Section: Pharmacologic Managementmentioning

confidence: 99%

Section: Pharmacologic Managementmentioning

confidence: 99%

Section: Pharmacologic Managementmentioning

confidence: 99%

Section: Pharmacologic Managementmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Infertility Management and Pharmacotherapy: What Every Pharmacist Should Know

Cieri‐Hutcherson

Harris

Karaoui

et al. 2020

Journal of Pharmacy Practice

View full text Add to dashboard Cite

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Prevalence and associated factors of medication adherence among infertile women undergoing frozen-thawed embryo transfer cycle: A cross-sectional study

Tong

et al. 2023

Front. Pharmacol.

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Objective: This study aimed to explore the prevalence and associated factors of medication adherence among infertile women undergoing frozen-thawed embryo transfer (FET) cycle.Methods: A cross-sectional study was conducted with 556 infertile women undergoing FET cycle in total. The Self-efficacy for Appropriate Medication Use Scale (SEAMS), Herth Hope Index (HHI) scale, and Social Support Rating Scale (SSRS) were used to evaluate the patients. Data were described by univariate and multivariate analyses. Logistic regression method was performed to analyse the factors potentially associated with medication adherence.Results: The average score of Self-efficacy for Appropriate Medication Use Scale (SEAMS) was 30.38 ± 6.65, and 65.3% of participants showed non-adherence. Multiple regression analysis indicated that first-time FET cycle, treatment stage, methods of daily medication, social support and hope level were the main associated factors of the medication adherence among infertile women undergoing FET cycle (p < 0.001).Conclusion: This study revealed the medication adherence is at medium level among infertile women undergoing FET cycle, especially in patients with repeated FET cycles. The study also suggested that improving the hope level and social support of infertile women undergoing FET cycle may increase medication adherence.

show abstract

Treatment of infertility in women

Cited by 2 publications

References 34 publications

Infertility Management and Pharmacotherapy: What Every Pharmacist Should Know

Infertility Management and Pharmacotherapy: What Every Pharmacist Should Know

Prevalence and associated factors of medication adherence among infertile women undergoing frozen-thawed embryo transfer cycle: A cross-sectional study

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