Treatment of Infections in Peritoneal Dialysis

Shetty, H G M; Gokal, Ram

doi:10.1159/000071390

Cited by 5 publications

(4 citation statements)

References 8 publications

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“…1,[2][3][4] In this study, we investigated the association of time of hospital admission, initial (present at the time of hospital admission) peritoneal neutrophil and lymphomononuclear cell profiles, clinical and laboratory parameters with the course of peritonitis, and the length of hospital stay because of peritonitis in PD patients.…”

Section: Discussionmentioning

confidence: 99%

“…[17][18][19] The incidence of culture-negative peritonitis, which may happen for a variety of technical or clinical reasons, in series ranges from 13.7 to 21%. 4,17 The incidence of culture-negative peritonitis is high in peritonitis attacks because of low virulence microorganisms or coagulase-negative staphylococci and may rise up to 20% in some series. 1,11 In our study, the incidence of culture-negative peritonitis was 28.7%, which was relatively higher than reported in the literature.…”

Section: Discussionmentioning

confidence: 99%

“…Although there have been improvements in CAPD techniques (including the Y-set and twin-bag systems) and patient education, recurrent peritonitis still remains the most common complication of CAPD therapy. 1,[2][3][4] Peritonitis is an important clinical problem in automated peritoneal dialysis (APD) patients as well. 5 The inflammatory response occurring during infection (peritonitis) is a multifaceted sequence of controlled events.…”

Section: Introductionmentioning

confidence: 99%

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Peritoneal cells at admission: do they have prognostic significance in peritonitis?

et al. 2010

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Peritonitis accounts for considerable morbidity and hospitalization in peritoneal dialysis (PD) patients. We investigated the factors related with time of hospital stay, especially focusing on the peritoneal cell profiles at the time of hospital admission in PD-related peritonitis. Eighty peritonitis attacks were evaluated. Data were collected at the time of hospital admission, clinical and biochemical parameters, including initial systemic and dialysate white cell counts (including percentage and differential count of neutrophils and lymphocytes) and length of hospital stay. Peritoneal leukocyte (r = +0.289, p = 0.009) and neutrophil counts (r = +0.403, p < 0.0001), peritoneal neutrophil percentage (r = +0.492, p < 0.0001), time of hospital admission (r = +0.498, p < 0.0001), and C-reactive protein (CRP) (r = +0.231, p = 0.042) were positively correlated; lymphomononuclear cell percentage (r = −0.650, p < 0.0001) was negatively correlated with hospitalization length. Hospital admission ≥24 hours of symptom onset was associated with higher CRP, dialysate leukocyte and neutrophil counts, longer hospitalization, and with lower dialysate lymphomononuclear cell percentage compared to admission <24 hours (p = 0.04, p = 0.04, p = 0.005, p < 0.0001, and p = 0.04, respectively). In multiple linear regression, the time of hospital admission (p = 0.002), initial peritoneal neutrophil count (p = 0.011), and lymphomononuclear cell percentage (p < 0.0001) were independently associated with hospitalization length. Hospital admission within first 24 hours of peritonitis symptoms onset is of vital importance; delayed admission is associated with higher peritoneal leukocyte and neutrophil counts, and increased length of hospital stay.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Peritoneal cells at admission: do they have prognostic significance in peritonitis?

et al. 2010

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“…Peritoneal dialysis (PD) represents an important therapeutic approach to chronic kidney disease (CKD), and its integration with other techniques ensures the optimization of the entire renal replacement therapy program [1]. Since Wilhelm Kolf in the early 1960s first reported the successful PD of a patient with CKD, this technique has continued to evolve, focusing on reduction of exit-site infection and peritonitis rates, optimal dialysis prescription, biocompatibility issues, catheters, and insertion technique [2].…”

Section: Introductionmentioning

confidence: 99%

Peritoneal Vicenza “Short” Catheter Outcomes and Comparison with International Society for Peritoneal Dialysis Guidelines

et al. 2021

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Introduction: A well-functioning peritoneal catheter is key to success of peritoneal dialysis (PD). The Vicenza “short” catheter is a modified Tenckhoff catheter with a shorter intraperitoneal segment. The aim of this study was to evaluate the incidence of catheter-related complications and catheter survival rate using the Vicenza “short” catheter, according to the goals suggested by the International Society for Peritoneal Dialysis (ISPD) guidelines. Second, we compared insertion techniques used in our center. Methods: This is a retrospective cohort, single-center study analyzing incident PD patients undergoing Vicenza “short” peritoneal catheter placement between January 1, 2015, and December 31, 2019. As clinical outcomes, we evaluated catheter patency at 12 months, exit-site/tunnel infection and peritonitis within 30 days of catheter insertion, visceral injury, or significant hemorrhage during the procedure, in accordance with ISPD guidelines. Results: The percentage of patency at 12 months for all catheter insertion methods was 88.91%, and the percentage for laparoscopic placement was 93.75%. The exit-site/tunnel infection and peritonitis occurring within 30 days of catheter insertion were, respectively, 0.75% and 2.2%; the visceral injury leading to intervention was 0.75%. We did not have any case of significant hemorrhage. All results were in line with ISPD guidelines. Conclusion: We conclude that the Vicenza “short” catheter is a suitable device for peritoneal access. The implantation procedure is safe and easy to perform, and both nephrologists and surgeons can do it. A confident use and a proper implantation of the Vicenza “short” catheter help achieve the clinical ISPD goals for the PD access procedure in terms of catheter survival and complication rates.

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Peritonitis

2015

Diagnostic Imaging: Gastrointestinal

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Treatment of Infections in Peritoneal Dialysis

Cited by 5 publications

References 8 publications

Peritoneal cells at admission: do they have prognostic significance in peritonitis?

Peritoneal cells at admission: do they have prognostic significance in peritonitis?

Peritoneal Vicenza “Short” Catheter Outcomes and Comparison with International Society for Peritoneal Dialysis Guidelines

Peritonitis

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