Treatment of infected bone defects with the induced membrane technique

Shen, Jie; Wei, Zhiyuan; Wang, Shulin; Wang, Xiaohua; Lin, Wei; Liu, Lei; Wang, Guanglin

doi:10.1302/2046-3758.129.bjr-2022-0439.r2

Cited by 5 publications

(3 citation statements)

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“…The comprehensive ability of students can be improved, and they can become the comprehensive talents needed in the new era. It can be seen that students' participation in the second classroom is very important and is related to their future long-term development [1].…”

Section: The Importance Of Student Participation In the Second Classroommentioning

confidence: 99%

Comparison of second class participation of vocational and general education students and analysis of influencing factors

2023

avte

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With the continuous development and progress of China's social economy, people's values have changed significantly. People gradually pay attention to the pursuit of spiritual culture, which brings new development opportunities and challenges for China's education industry. If the education industry wants to withstand the test of the times, it should be brave to innovate. For the education industry, whether it is vocational undergraduate colleges and universities or ordinary undergraduate colleges and universities, the best way to realize innovation is to strengthen their own training in the comprehensive quality of students. The creation of the second classroom can effectively achieve this effect, and promote the improvement of students' comprehensive quality through activity education. This paper first summarizes the importance of students' participation in the second classroom and the comparison of the second classroom participation of vocational undergraduate students and the factors affecting it, and elaborates on the effective strategies to improve the enthusiasm of vocational undergraduate students' participation in the second classroom from various aspects. We hope this paper can have certain reference value.

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Section: The Importance Of Student Participation In the Second Classroommentioning

confidence: 99%

Comparison of second class participation of vocational and general education students and analysis of influencing factors

2023

avte

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“…2,3 Since the two-stage operation required for the IMT is consistent with first-stage infection control and second-stage bone reconstruction, it is especially advantageous in treating infected bone defects. 4,5…”

Section: Introductionmentioning

confidence: 99%

The induced membrane technique for the management of infected segmental bone defects

Shen,

Wei,

et al. 2024

Bone Joint J

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AimsThe aim of the present study was to assess the outcomes of the induced membrane technique (IMT) for the management of infected segmental bone defects, and to analyze predictive factors associated with unfavourable outcomes.MethodsBetween May 2012 and December 2020, 203 patients with infected segmental bone defects treated with the IMT were enrolled. The digital medical records of these patients were retrospectively analyzed. Factors associated with unfavourable outcomes were identified through logistic regression analysis.ResultsAmong the 203 enrolled patients, infection recurred in 27 patients (13.3%) after bone grafting. The union rate was 75.9% (154 patients) after second-stage surgery without additional procedures, and final union was achieved in 173 patients (85.2%) after second-stage surgery with or without additional procedures. The mean healing time was 9.3 months (3 to 37). Multivariate logistic regression analysis of 203 patients showed that the number (≥ two) of debridements (first stage) was an independent risk factor for infection recurrence and nonunion. Larger defect sizes were associated with higher odds of nonunion. After excluding 27 patients with infection recurrence, multivariate analysis of the remaining 176 patients suggested that intramedullary nail plus plate internal fixation, smoking, and an allograft-to-autograft ratio exceeding 1:3 adversely affected healing time.ConclusionThe IMT is an effective method to achieve infection eradication and union in the management of infected segmental bone defects. Our study identified several risk factors associated with unfavourable outcomes. Some of these factors are modifiable, and the risk of adverse outcomes can be reduced by adopting targeted interventions or strategies. Surgeons can fully inform patients with non-modifiable risk factors preoperatively, and may even use other methods for bone defect reconstruction.Cite this article: Bone Joint J 2024;106-B(6):613–622.

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“…3 The rate of infection recurrence is lower with the Chongqing technique than that of traditional internal fixation methods. 7 Being different from external fixation, the Chongqing technique is free of pin-track infection, 8 and better at maintaining joint function and daily life. 3,9 In addition, they are both quite effective in infection control.…”

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confidence: 99%