Treatment of hypopigmented burn hypertrophic scars with short‐term topical tacrolimus does not lead to repigmentation
Esteban A. Molina,
Taryn E. Travis,
Lou'ay Hussein
et al.
Abstract:ObjectivesDyschromia is an understudied aspect of hypertrophic scar (HTS). The use of topical tacrolimus has successfully shown repigmentation in vitiligo patients through promotion of melanogenesis and melanocyte proliferation. It was hypothesized that HTSs treated with topical tacrolimus would have increased repigmentation compared to controls.MethodologyFull‐thickness burns in red Duroc pigs were either treated with excision and meshed split‐thickness skin grafting or excision and no grafting, and these wou… Show more
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